(R)-Synephrine

Name: (R)-Synephrine
SKU: S9755
Availability: InStock

Product ID S9755

Cas No. 614-35-7

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Synephrine is an endogenous alkaloid that can also be found in citrus fruits, Evodia, and Zanthoxylum. Synephrine exhibits vasoconstrictive, anti-inflammatory, antibacterial, and gastrointestinal motility modulating activities. Synephrine acts as a positive inotrope, activating adrenergic receptors (displaying partial selectivity for α-adrenergic receptors), TAAR-1 receptors, and 5-HT receptors. Synephrine decreases levels of ROS, activity of myeloperoxidase, infiltration of inflammatory cells, and expression of TNF-α and IL-6 in the lungs of animal models of lung injury and inflammation. Additionally, synephrine inhibits gastrointestinal motility and slows gastric emptying.

Product Info

Cas No.	614-35-7
Purity	≥98%
Formula	C₉H₁₃NO₂
Formula Wt.	167.21
IUPAC Name	[(2R)-2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylazanium
Synonym	R(-)-Synephrine; D-(-)-Synephrine; (-)-Oxedrine
Melting Point	162-164°C
Appearance	White to off white powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	S9755 MSDS PDF
Info Sheet	S9755 Info Sheet PDF

References

Wu Q, Li R, Soromou LW, et al. p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway. Inflamm Res. 2014 Jun;63(6):429-39. PMID: 24487736.

Ozçelik B, Kartal M, Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402. PMID: 21391841.

Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med. 2009 Jan;75(1):24-31. PMID: 19016407.

Endoh M, Schümann HJ, Krappitz N, et al. alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. Jpn J Pharmacol. 1976 Apr;26(2):179-90. PMID: 7694.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Comments
This field is for validation purposes and should be left unchanged.

(R)-Synephrine

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Baccatin VI

GDC-0068

Neurokinin A (4-10)

Nisoldipine

Neosolaniol

Cilostazol

Uracil

Penicillic Acid

L-5-Hydroxytryptophan

Nidulal

Verubecestat

Thienylpentyl Isothiocyanate

RGDC

Dermorphin

Repaglinide

Loperamide Hydrochloride

Rivastigmine Tartrate

Bactenecin

Calcium Folinate Pentahydrate

Secretin, human

Footer