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Rebamipide

Rebamipide

Product ID R1806
Cas No. 90098-04-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $81.70 In stock
5 g $337.10 In stock
25 g $826.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Rebamipide is a quinolone derivative that is clinically used for mucosal protection in the treatment of gastritis and ulcers. Rebamipide exhibits antioxidative activity as a radical scavenger and inhibits NSAID-induced lipid peroxidation, alterations in mitochondrial membrane potential, and apoptosis in epithelial cells.

Product Info

Cas No.

90098-04-7

Purity

≥98%

Formula

C19H15ClN2O4

Formula Wt.

370.79

Chemical Name

α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid

IUPAC Name

2-[(4-chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid

Synonym

Proamipide, OPC-12759, Mucosta

Melting Point

288-290°C(dec)

Solubility

Soluble in dimethyl- formamide, DMSO (74mg/mL). Slightly soluble in water, methanol and ethanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R1806 MSDS PDF

Info Sheet

R1806 Info Sheet PDF

References

Nagano Y, Matsui H, Muramatsu M, et al. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Dig Dis Sci. 2005 Oct;50 Suppl 1:S76-83. PMID: 16184425.

Arakawa T, Kobayashi K, Yoshikawa T, et al. Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing. Dig Dis Sci. 1998 Sep;43(9 Suppl):5S-13S. PMID: 9753220.

Arakawa T, Watanabe T, Fukuda T, et al. Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine. Dig Dis Sci. 1995 Nov;40(11):2469-72. PMID: 7587834.

Custom Order

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