Description
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
| Cas No. | 34388-59-5 |
|---|---|
| Purity | ≥95% |
| Formula | C15H24N6O2 |
| Formula Wt. | 320.4 |
| IUPAC Name | N5-(Diaminomethylene)-L-ornithyl-L-phenylalaninamide |
| Synonym | RF amide peptide |
| Solubility | Soluble in water. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.
Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.
Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.
ACE inhibitor.
FLT3, PDGFR, c-Kit inhibitor.
Cytarabine derivative, nucleoside (cytosine) an...
Endogenous peptide, involved in vasoconstrictio...
Topoisomerase II inhibitor, RPA modulator.
Diterpene found in coffee beans.
Nitrogen mustard and estradiol derivative; micr...
Taxane found in Taxus; potential microtubule de...
Analog of rapamycin.
Endogenous peptide hormone fragment, involved i...
Abl, PDGFR, EphR, Src, k-Kit, FYN, LCK, HCK inh...
Sesquiterpene lactone found in Saussurea.
Triterpene saponin found in Dipsacus asper.
Phytoestrogen, isoflavone found in various plan...
Protease inhibitor.
Synthetic ITC.
Pyrimidine, glucose analog, used to induce diab...
Endogenous steroid hormone, estradiol metabolit...
ITC found in Nasturtium officinale (watercress)...