Description
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
Cas No. | 34388-59-5 |
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Purity | ≥95% |
Formula | C15H24N6O2 |
Formula Wt. | 320.4 |
IUPAC Name | N5-(Diaminomethylene)-L-ornithyl-L-phenylalaninamide |
Synonym | RF amide peptide |
Solubility | Soluble in water. |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet |
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Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.
Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.
Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.
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