Description
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
| Cas No. | 34388-59-5 |
|---|---|
| Purity | ≥95% |
| Formula | C15H24N6O2 |
| Formula Wt. | 320.4 |
| IUPAC Name | N5-(Diaminomethylene)-L-ornithyl-L-phenylalaninamide |
| Synonym | RF amide peptide |
| Solubility | Soluble in water. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.
Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.
Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.
Triazole; demethylation inhibitor, NMDA agonist...
NSAID; COX-1/2 inhibitor.
IMPDH inhibitor.
Nitrogen mustard, DNA alkylator.
Organosulfur, antioxidant.
Diacerein metabolite, anthraquinone found in Rh...
Polyether Ca2+ ionophore.
Oltipraz analog, salivary gland secretion enhan...
Used to study embryonic cloning; microtubule po...
Flavonoid glycoside found in Scutellaria.
RAF inhibitor.
Thiazolidinedione; PPARγ agonist.
Prevents MHC II antigen presentation.
Thiazolidinedione; PPARγ agonist.
ACE inhibitor.
Indole, glucosinolate found in cruciferous vege...
5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...
Dienolide kavalactone originally found in Piper...
Cyclic peptide; calcineurin inhibitor.
SIRT inhibitor.