Description
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
| Cas No. | 34388-59-5 |
|---|---|
| Purity | ≥95% |
| Formula | C15H24N6O2 |
| Formula Wt. | 320.4 |
| IUPAC Name | N5-(Diaminomethylene)-L-ornithyl-L-phenylalaninamide |
| Synonym | RF amide peptide |
| Solubility | Soluble in water. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.
Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.
Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.
Lck, Src, SIK inhibitor.
NSAID; COX-1/2 and lipoxygenase inhibitor.
Impurity of everolimus
Alkaloid found in Catharanthus, precursor in sy...
Endogenous opioid peptide; μOR agonist.
L-type and T-type Ca2+ and TRP antagonist.
Inhibitor of BMP.
Sulfur analog of furan found in cooked meat pro...
MET inhibitor.
Diterpenoid epoxide found in Tripterygium.
5-HT2A and TRPV1 antagonist, potential α1-adre...
Cyclosporin metabolite; weak calmodulin inhibit...
Cdc42 inhibitor.
Polyene, binds ergosterol and induces membrane ...
TRPC5 activator, NS4B and histamine H1 inhibito...
EZH2 HMT inhibitor.
Secoiridoid glycoside found in Gentiana and Cep...
Basic phenol skeleton structure found in variou...
Nucleoside (deoxyguanosine) analog; DNA chain t...
Cyclosporin metabolite; formyl peptide inhibito...