| Product Unit Size | Cost | Quantity | Stock |
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S-(-)-Carbidopa is a hydrazine that inhibits L-amino acid decarboxylase; it only acts peripherally when given systemically, as it does not cross the blood-brain barrier. S-(-)-Carbidopa inhibits formation of dopamine granules and dopamine-mediated swimming activity in sea urchins. In animal models with mutant isoforms of dopamine β-hydroxylase, S-(-)-carbidopa inhibits restoration of norepinephrine and other catecholamine production through rescue treatments.
| Cas No. | 38821-49-7 |
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| Purity | ≥98% |
| Formula | C10H14N2O4 • H2O |
| Formula Wt. | 244.24 |
| IUPAC Name | (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid;hydrate |
| Appearance | White to off white powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Katow H, Suyemitsu T, Ooka S, et al. Development of a dopaminergic system in sea urchin embryos and larvae. J Exp Biol. 2010 Aug 15;213(Pt 16):2808-19. PMID: 20675551.
Thomas SA, Marck BT, Palmiter RD, et al. Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. J Neurochem. 1998 Jun;70(6):2468-76. PMID: 9603211.