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Tazobactam

Tazobactam

Product ID T0298
Cas No. 89786-04-9
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $92.00 In stock
500 mg $296.30 In stock
1 g $510.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
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  • Downloads
  • References
  • Custom Order

Description

Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.

Product Info

Cas No.

89786-04-9

Purity

≥98%

Formula

C10H12N4O5S

Formula Wt.

300.29

Chemical Name

(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1- ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide

IUPAC Name

(2S,3S,5R)-3-methyl-4,4, 7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane- 2-carboxylic acid

Synonym

YTR-830H, CL-298741

Melting Point

170-178°C

Solubility

water, methanol

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T0298 MSDS PDF

Info Sheet

T0298 Info Sheet PDF

References

Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.

Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.

Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.

Custom Order

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