Description
Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.
Product Unit Size | Cost | Quantity | Stock |
---|
Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.
Cas No. | 89786-04-9 |
---|---|
Purity | ≥98% |
Formula | C10H12N4O5S |
Formula Wt. | 300.29 |
Chemical Name | (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1- ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide |
IUPAC Name | (2S,3S,5R)-3-methyl-4,4, 7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane- 2-carboxylic acid |
Synonym | YTR-830H, CL-298741 |
Melting Point | 170-178°C |
Solubility | water, methanol |
Appearance | White Crystal Powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.
Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.
Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.
Proton pump inhibitor
NSAID; COX-1/2 and lipoxygenase inhibitor.
Cap-dependent endonuclease inhibitor
FLT3, c-Kit, PDGFR inhibitor.
Nucleoside (deoxycytidine) analog; ribonucleoti...
Alkaloid found in Catharanthus, precursor in sy...
Synthetic fluorinated thiamphenicol analog; pro...
p110α PI3K inhibitor.
Pentacyclic triterpene found in various plant s...
T-type calcium channel blocker
Cyclic sesquiterpene found in ginger root; pote...
Docetaxel impurity
PARP1/2 inhibitor.
Monoterpene found in various plant sources.
Endogenous peptide neurotransmitter, involved i...
Aminopropyl carbazole, neuroprotective.
NSAID; TRPA1 agonist, COX-2 inhibitor.
Lck, Src, SIK inhibitor.
Polyether Ca2+ ionophore.
ET-A/B antagonist.