Tetracycline

Name: Tetracycline
SKU: T1677
Availability: InStock

Product ID T1677

Cas No. 60-54-8

Purity ≥90%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Tetracycline is a polyketide antibiotic originally produced by Streptomyces that exhibits antibacterial and neuroprotective activities. Tetracycline binds the 30S subunit of the bacterial ribosome, preventing aminoacyl-tRNA from binding to the ribosomal A site and inhibiting protein synthesis. Tetracycline is clinically used to treat acne, rosacea, Lyme disease, and various bacterial infections. Tetracycline binds amyloid-β (Aβ) peptides, increasing their solubility and decreasing their neurotoxicity in vitro. Tetracycline may also inhibit matrix metalloproteinases (MMPs). Additionally, tetracycline inhibits mammalian RNA splicing.

Product Info

Cas No.	60-54-8
Purity	≥90%
Formula	C₂₂H₂₄N₂O₈
Formula Wt.	444.43
Chemical Name	[4S-(4α,4aα,5aα,6b,12aα)]-4-(Dimethylamino)-1,4,4a,-5,5a,6-11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
IUPAC Name	4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5, 5a-tetrahydrotetracene-2-carboxamide
Synonym	Deschlorobiomycin, Ambramycin, Liquamycin
Melting Point	170-175°C(dec)
Solubility	Soluble in methanol or ethanol (20 mg/mL). Slightly soluble in water (0.4 mg/mL).
Appearance	Yellow Crystal Powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	T1677 MSDS PDF
Info Sheet	T1677 Info Sheet PDF

References

Kennedy R, Alibhai M, Shakib K. Tetracycline: a cure all? Br J Oral Maxillofac Surg. 2014 Apr;52(4):382-3. PMID: 24613100.

Mahajan GB, Balachandran L. Antibacterial agents from actinomycetes - a review. Front Biosci (Elite Ed). 2012 Jan 1;4:240-53. PMID: 22201868.

Airoldi C, Colombo L, Manzoni C, et al. Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction. Org Biomol Chem. 2011 Jan 21;9(2):463-72. PMID: 21063627.

Griffin MO, Fricovsky E, Ceballos G, et al. Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010 Sep;299(3):C539-48. PMID: 20592239.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Tetracycline

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

DAMGO

Somatostatin-14

7-epi-10-Deacetyltaxol

Chondroitin Sulfate, cow

2″,3″-Dihydrocephalomannine

Tirasemtiv

Doxifluridine

Concanavalin A

Methylprednisolone

4-Phenylbutylisothiocyanate

Nigericin Sodium

19-O-Desmethoxy rapamycin

Myclobutanil

Diclofenac Sodium

Carbinoxamine Maleate

(R)-P7C3-OMe

3-Methyladenine

Vapreotide

Pyrantel Pamoate

N-Des-2-methylpropan-2-ol Docetaxel

Footer