LKT Labs

Biochemicals for Life Science Research

Theaflavin-3-gallate

Theaflavin-3-gallate

Product ID T286165
Cas No. 30462-34-1
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $157.50 In stock
5 mg $630.00 In stock
Bulk Quote

Quicklinks

Description

Theaflavin-3-gallate is a polyphenolic compound found in black tea. The theaflavins are formed during the enzymatic oxidation of catechins, which happens during processing of the fresh tea leaves. Theaflavin-3-gallate has been shown to have inhibitory effects on ovarian cancer cells OVCAR-3 and A2780/CP70 by inducing apoptosis and impairing tumor angiogenesis. In addition, theaflavin-3-gallate was found to give stronger reactive oxygen species scavenging activity than theaflavin by a chemiluminescence assay. Exposure of CAL27 and HSC-2 carcinoma cells to theaflavin-3-gallate demostrated cytotoxic and antiproliferative properties of the compound.

Product Info

Cas No.

30462-34-1
Purity

≥95%
Formula

C36H28O16
Formula Wt.

716.60
IUPAC Name

(2R,3R)-5,7-Dihydroxy-2-{3,4,5-trihydroxy-6-oxo-1-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-6H-benzo[7]annulen-8-yl}-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

T286165 MSDS PDF
Info Sheet

T286165 Info Sheet PDF

References

Gao Y, Rankin GO, Tu Y, et al. Inhibitory effects of the four main theaflavin derivatives found in black tea on ovarian cancer cells. Anticancer Res. 2016 Feb;36(2):643-651. PMID: 26851019.

Wu YY, Li W, Xu Y, et al. Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence adn DNA damage analyses. J Zhejiang Univ Sci B. 2011 Sep;12(9):744-751. PMID: 21887850.

Babich H, Gottesman RT, Liebling EJ, et al. Theaflavin-3-gallate and theaflavin-3’-gallate, polyphenols in black tea with prooxidant properties. Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):66-74. PMID: 18346048.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A0099

    A-779

    Mas antagonist.

    ≥95%
  • V182685

    Verdinexor

    CRM1/XPO1 inhibitor.

    ≥99%
  • E6257

    Epothilone B

    Microtubule depolymerization inhibitor.

    ≥98%
  • P2510

    4-Phenylbutylisothiocyanate

    Synthetic ITC.

    ≥98%
  • E0003

    E64-d

    Cathepsin inhibitor.

    ≥97%
  • G733400

    GSK-2578215A

    Selective inhibitor of LRRK2.

    ≥98%
  • A9712

    AZD-6482

    p110β PI3K inhibitor.

    ≥98%
  • C0016

    Caerulomycin A

    Bipyridamine toxin.

    ≥96%
  • G3453

    20(S)-Ginsenoside Rh2

    Triterpene saponin found in Panax.

    ≥98%
  • C3446

    Cilnidipine

    Dihydropyridine; L-type and N-type Ca2+ channel...

    ≥98%
  • E5575

    Entacapone

    COMT inhibitor.

    ≥98%
  • I4934

    Imipenem Monohydrate

    Carbapenem β-lactam; penicillin binding protei...

    ≥98%
  • C9809

    Cyclopiazonic Acid

    SERCA inhibitor.

    ≥98%, TLC
  • M1769

    Meropenem Trihydrate

    β-lactam carbapenem; penicillin binding protei...

    ≥98%
  • T3040

    Thienylpentyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • M002698

    M2698

    Dual inhibitor of p70S6K and Akt.

    ≥99%
  • P3600

    PJ34 Hydrochloride

    PARP inhibitor; potential Pim1 inhibitor.

    ≥95%
  • G7232

    GS-9973

    Syk inhibitor.

    ≥98%
  • O4672

    Olsalazine Sodium

    5-Aminosalicylate prodrug, NSAID; COX-1/2 inhib...

    ≥98%
  • R3310

    Ricobendazole

    Nitroimidazole; microtubule polymerization inhi...

    ≥98%