LKT Labs

Biochemicals for Life Science Research

Theaflavin-3-gallate

Theaflavin-3-gallate

Product ID T286165
Cas No. 30462-34-1
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $157.50 In stock
5 mg $630.00 In stock
Bulk Quote

Quicklinks

Description

Theaflavin-3-gallate is a polyphenolic compound found in black tea. The theaflavins are formed during the enzymatic oxidation of catechins, which happens during processing of the fresh tea leaves. Theaflavin-3-gallate has been shown to have inhibitory effects on ovarian cancer cells OVCAR-3 and A2780/CP70 by inducing apoptosis and impairing tumor angiogenesis. In addition, theaflavin-3-gallate was found to give stronger reactive oxygen species scavenging activity than theaflavin by a chemiluminescence assay. Exposure of CAL27 and HSC-2 carcinoma cells to theaflavin-3-gallate demostrated cytotoxic and antiproliferative properties of the compound.

Product Info

Cas No.

30462-34-1
Purity

≥95%
Formula

C36H28O16
Formula Wt.

716.60
IUPAC Name

(2R,3R)-5,7-Dihydroxy-2-{3,4,5-trihydroxy-6-oxo-1-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-6H-benzo[7]annulen-8-yl}-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

T286165 MSDS PDF
Info Sheet

T286165 Info Sheet PDF

References

Gao Y, Rankin GO, Tu Y, et al. Inhibitory effects of the four main theaflavin derivatives found in black tea on ovarian cancer cells. Anticancer Res. 2016 Feb;36(2):643-651. PMID: 26851019.

Wu YY, Li W, Xu Y, et al. Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence adn DNA damage analyses. J Zhejiang Univ Sci B. 2011 Sep;12(9):744-751. PMID: 21887850.

Babich H, Gottesman RT, Liebling EJ, et al. Theaflavin-3-gallate and theaflavin-3’-gallate, polyphenols in black tea with prooxidant properties. Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):66-74. PMID: 18346048.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A7203

    AS-703026

    MEK1/2 inhibitor.

    ≥98%
  • C5592

    CNX-774

    BTK inhibitor.

    ≥98%
  • S1843

    L-Selectin

    Endogenous adhesion molecule, binds PKC, calmod...

    ≥95%
  • C0253

    Candesartan

    AT1 inhibitor.

    ≥98%
  • M2408

    MGCD-265 Analog

    MET inhibitor.

    ≥98%
  • W0269

    (±)-Warfarin

    Coumarin; VKORC1 inhibitor.

    ≥98%
  • E6356

    Epothilone D

    Microtubule depolymerization inhibitor.

    ≥98%
  • O486179

    Omeprazole Impurity C

    Impurity of omeprazole

    ≥99%
  • D3431

    3,4-Dihydroxyphenyl Ethanol

    Polyphenol found in olive oil, antioxidant.

    ≥95%
  • F4582

    Fluocinolone Acetonide

    Synthetic hydrocortisone derivative; glucocorti...

    ≥98%
  • A2054

    Aflatoxin M2

    Mycotoxin produced by species of Aspergillus; D...

    ≥98%
  • U6956

    Uroguanylin, human

    Endogenous peptide, involved in water/Na+ homeo...

    ≥95%
  • P7219

    Pseudolaric Acid B

    Diterpene acid found in Pseudolarix kaempferi.<...

    ≥98%
  • P3568

    Pirarubicin

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • H3278

    HIV Reverse Transcriptase A2.1 Peptide

    Peptide, HIV-1 RT A2.1 epitope.

    ≥95%
  • I4962

    Isoimperatorin

    Furocoumarin; COX-2 inhibitor.

    ≥98%
  • R0109

    Racecadotril

    Enkephalinase inhibitor.

    ≥98%
  • I7759

    Isoxanthohumol

    Prenylflavinoid, derivative of xanthohumol foun...

    ≥98%
  • O486188

    Omeprazole Impurity F and G mixture

    Regioisomers

    ≥98%
  • P1853

    Penicillin V Potassium

    Hydrophobic β-lactam; penicillin binding prote...

    ≥98%