Theaflavin-3,3’-digallate

Name: Theaflavin-3,3’-digallate
SKU: T286163
Availability: InStock

Product ID T286163

Cas No. 30462-35-2

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Theaflavin-3,3’-digallate is a polyphenolic compound found in black tea. The theaflavins are formed during the enzymatic oxidation of catechins, which happens during processing of the fresh tea leaves. Theaflavin-3,3’-digallate has also shown inhibitory effects on ovarian cancer cells OVCAR-3 and A2780/CP70 by inducing apoptosis and impairing tumor angiogenesis. In addition, theaflavin-3,3’-digallate was found to produce notably efficient reactive oxygen species scavenging activity by a chemiluminescence assay. Theaflavin-3,3’-digallate was also shown to produce chemopreventive effects through the inhibition of the EGFR signaling pathway as a result of EGFR down-regulation.

Product Info

Cas No.	30462-35-2
Purity	≥98%
Formula	C₄₃H₃₂O₂₀
Formula Wt.	868.71
Chemical Name	[(2R,3R)-2-[1-[(2R,3R)-5,7-Dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,5-trihydroxy-6-oxobenzo[7]annulen-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
IUPAC Name	(3,4,5-Trihydroxy-6-oxo-6H-benzo[7]annulene-1,8-diyl)bis[(2R,3R)-5,7-dihydroxy-3,4-dihydro-2H-chromene-2,3-diyl] bis(3,4,5-trihydroxybenzoate)
Synonym	Theaflavin digallate
Melting Point	226-230°C dec
Solubility	0.1 mg/mL water.
Appearance	Brick red powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	T286163 MSDS PDF
Info Sheet	T286163 Info Sheet PDF

References

Gao Y, Rankin GO, Tu Y, et al. Inhibitory effects of the four main theaflavin derivatives found in black tea on ovarian cancer cells. Anticancer Res. 2016 Feb;36(2):643-651. PMID: 26851019.

Wu YY, Li W, Xu Y, et al. Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence adn DNA damage analyses. J Zhejiang Univ Sci B. 2011 Sep;12(9):744-751. PMID: 21887850.

Mizuno H, Cho YY, Zhu F, et al. Theaflavin-3,-3’-digallate induces epidermal growth factor receptor downregulation. Mol Carcinog. 2006 Mar;45(3):204-212. PMID: 16353237.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Theaflavin-3,3’-digallate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Potassium Canrenoate

S-(−)-Schisandrin B

Ligustrazine Hydrochloride

RGW-611

L-Cystine

17-Allylaminogeldanamycin

Baccatin VI

Thapsigargin

Apoptosis Activator 2

Kyotorphin

Syntide 2

17-Dimethylaminoethylamino Demethoxygeldanamycin

K252a

Small Cardioactive Peptide B

Idoxuridine

Evacetrapib

Argipressin Acetate

CCT-245737

Deferasirox

BMS-708163

Footer