• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Thymopentin

Thymopentin

Product ID T3093
Cas No. 69558-55-0
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $245.30 Please Inquire
10 mg $417.10 Please Inquire
25 mg $735.90 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Thymopentin is a synthetic, immunomodulatory pentapeptide (thymopoietin, 32-36). In animal models of experimental autoimmune encephalitis (EAE), thymopentin decreases phosphorylation of IκB kinase and inhibits production of HSP72, lessening disease severity. In other models, thymopentin decreases iNOS expression and activity, exhibiting potential anticancer chemotherapeutic benefit in the treatment of Sezary syndrome. In macrophages, this compound increases activation of NF-κB. In other in vitro models, thymopentin binds to MHC II HLA-DR complexes and modulates T cell activity.

Product Info

Cas No.

69558-55-0

Purity

≥95%

Formula

C30H49N9O9

Formula Wt.

679.8

IUPAC Name

(3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid

Synonym

TP-5, RKDVY

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T3093 MSDS PDF

Info Sheet

T3093 Info Sheet PDF

References

Lunin SM, Glushkova OV, Khrenov MO, et al. Thymic peptides restrain the inflammatory response in mice with experimental autoimmune encephalomyelitis. Immunobiology. 2013 Mar;218(3):402-7. PMID: 22727332.

Patruno A, Tosco P, Borretto E, et al. Thymopentin down-regulates both activity and expression of iNOS in blood cells of Sézary syndrome patients. Nitric Oxide. 2012 Oct 15;27(3):143-9. PMID: 22721692.

Lunin SM, Glushkova OV, Khrenov MO, et al. Thymus peptides regulate activity of RAW 264.7 macrophage cells: inhibitory analysis and a role of signal cascades. Expert Opin Ther Targets. 2011 Dec;15(12):1337-46. PMID: 22148922.

Liu Z, Zheng X, Wang J, et al. Molecular analysis of thymopentin binding to HLA-DR molecules. PLoS One. 2007 Dec 26;2(12):e1348. PMID: 18159232.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A2401

    AG-18

    EGFR and PDGFR inhibitor

    ≥98%
  • I7759

    Isoxanthohumol

    Prenylflavinoid, derivative of xanthohumol foun...

    ≥98%
  • P7060

    Protocatechuic Acid Ethyl Ester

    Dihydroxyphenolic acid found in cruciferous veg...

    ≥98%
  • N3450

    Nimesulide

    NSAID; COX-2 inhibitor.

    ≥98%
  • S584780

    Sotorasib racemate

    KRAS inhibitor

    ≥99%
  • H6225

    HPGDS-inhibitor-1

    HPGDS inhibitor.

    ≥98%
  • H1662

    HER2/neu (654-662) GP2

    Peptide fragment of HER2/neu/erbB2 receptor.

    ≥95%
  • V0376

    Vatalanib Dihydrochloride

    VEGFR inhibitor.

    ≥98%
  • M9645

    Myelin Oligodendrocyte Glycoprotein (35-55), rat

    Oligodendrocyte antigen used to induce EAE.

    ≥95%
  • C4756

    Cloxacillin Sodium Monohydrate

    β-lactam; penicillin binding protein inhibitor...

    ≥98%
  • D0808

    DCC-2036

    Abl inhibitor.

    ≥98%
  • A5275

    [Des-Asp1]-Angiotensin I, human

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • J8800

    JW55

    TNKS1/2 inhibitor.

    ≥98%
  • F4501

    Flavanone

    Variety of flavonoid found in various plant sou...

    ≥98%
  • V0352

    Vandetanib

    RET, EGFR, VEGFR2 inhibitor.

    ≥98%
  • C3477

    Citalopram Hydrobromide

    SERT inhibitor.

    ≥98%
  • B0108

    Bactenecin

    Cathelicidin derivative, antimicrobial peptide,...

    ≥95%
  • E6396

    EPZ005687

    EZH2 HMT inhibitor.

    ≥99%
  • L960010

    LY-3200882

    TGF-β1 inhibitor.

    ≥98%
  • A5044

    Amlodipine Besylate

    Dihydropyridine, FIASMA; L-type Ca2+ channel bl...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only