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Thymosin β-4 is an endogenous pro-angiogenic, fibroblast-activating peptide that is involved in hormone regulation. Thymosin β-4 also exhibits immunomodulatory and cardioprotective activities. Thymosin β-4 improves would healing in cardiac issue and improves cardiac function in vivo. Thymosin β-4 binds G-actin filaments, preventing actin polymerization.
| Cas No. | 77591-33-4 |
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| Purity | ≥85% |
| Formula | C212H350N56O78S |
| Formula Wt. | 4963.49 |
| Synonym | Thymosin β4 |
| Solubility | Soluble in water (1 mg/mL). |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
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| Info Sheet |
Qian L, Huang Y, Spencer CI, et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature. 2012 May 31;485(7400):593-8. PMID: 22522929.
Wolfe MW, Vakharia DD, Wise TH, et al. Characterization of secretion of thymosin alpha 1 and thymosin beta 4 during prepuberty, estrus and pregnancy in the bovine female. Domest Anim Endocrinol. 1989 Jan;6(1):71-8. PMID: 2917466.