LKT Labs

Biochemicals for Life Science Research

Thyrotropin-releasing Hormone

Thyrotropin-releasing Hormone

Product ID T3100
Cas No. 24305-27-9
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $81.70 In stock
10 mg $138.90 In stock
25 mg $245.30 In stock
Bulk Quote

Quicklinks

Description

Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide amide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and neuroprotective activities. TRH prevents oxidative stress, caspase-mediated apoptosis, glutamate toxicity, and neuroinflammation. Additionally, TRH stimulates epidermal regeneration in ex vivo models, activating would healing. TRH activates the TRH receptor.

Product Info

Cas No.

24305-27-9
Purity

≥95%
Formula

C16H22N6O4
Formula Wt.

362.4
Synonym

TRH, Thyrotropin-releasing factor, TRF, Protirelin, Thyroliberin
Solubility

Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

T3100 MSDS PDF
Info Sheet

T3100 Info Sheet PDF

References

Fekete C, Lechan RM. Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. Endocr Rev. 2013 Dec 4:er20131087. [Epub ahead of print]. PMID: 24423980.

Pekary AE, Sattin A. Increased TRH and TRH-like peptide release in rat brain and peripheral tissues during proestrus/estrus. Peptides. 2013 Dec 1;52C:1-10. PMID: 24296042.

Daimon CM, Chirdon P, Maudsley S, et al. The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. Am J Alzheimers Dis (Columbia). 2013;1(1). PMID: 24199031.

Meier NT, Haslam IS, Pattwell DM, et al. Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin. PLoS One. 2013 Sep 2;8(9):e73596. PMID: 24023889.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R2510

    RGD-4C

    Peptide, used to deliver conjugated drugs to ce...

    ≥95%
  • B5609

    Boc-GRR-AMC

    Peptide, protease substrate.

    ≥98%
  • B1870

    Berberine Chloride

    Isoquinoline alkaloid found in various plant so...

    ≥97%
  • H014458

    Halometasone

    Glucocorticoid

    ≥98%
  • B1853

    1,4-Benzoquinone

    Precursor in the synthesis of hydroquinone, ant...

    ≥98%
  • C0250

    Calcitonin Gene Related Peptide II, human

    Calcitonin-family peptide, involved in vasodila...

    ≥95%
  • D1759

    Deoxynivalenol

    Trichothecene mycotoxin produced by Fusarium.

    ≥98%, TLC
  • M4000

    MK-2206 Monohydrochloride

    Akt inhibitor.

    ≥99%
  • I7557

    1-Isothiocyanato-6-(methylsulfonyl)-hexane

    Synthetic ITC, erysolin analog.

    ≥98%
  • I7074

    Irsogladine Maleate

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • A4400

    Alamethicin

    Antimicrobial peptide found in Trichoderma, ind...

    ≥95%
  • L2876

    Luteinizing Hormone Releasing Hormone III, lamprey

    Peptide hormone found in eels; GnRH agonist, we...

    ≥98%
  • V3378

    Vitamin B12

    Coenzyme, vitamin found in dairy, meat, eggs, f...

    ≥97%
  • C2961

    Chondroitin Sulfate, chicken

    Polyanionic sulfated glycosaminoglycan, endogen...

    ≥90%
  • A4515

    Alendronate Monosodium Trihydrate

    Bisphosphonate.

    ≥98%
  • A5314

    Dehydroandrographolide

    Labdane diterpene found in Andrographis.

    ≥98%
  • C000082

    C-82

    beta-catenin inhibitor

    ≥99%
  • M9646

    Myelin Basic Protein (68-82), guinea pig

    Immunodominant peptide epitope occurring in mul...

    ≥95%
  • E6231

    (−)-Epicatechin

    Flavanol originally found in Camilla (green tea...

    ≥93%
  • W0270

    (±)-Warfarin Sodium Clathrate

    Coumarin; VKORC1 inhibitor.

    ≥98%