LKT Labs

Biochemicals for Life Science Research

Thyrotropin-releasing Hormone

Thyrotropin-releasing Hormone

Product ID T3100
Cas No. 24305-27-9
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $82.00 In stock
10 mg $139.00 In stock
25 mg $245.00 In stock
Bulk Quote

Quicklinks

Description

Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide amide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and neuroprotective activities. TRH prevents oxidative stress, caspase-mediated apoptosis, glutamate toxicity, and neuroinflammation. Additionally, TRH stimulates epidermal regeneration in ex vivo models, activating would healing. TRH activates the TRH receptor.

Product Info

Cas No.

24305-27-9
Purity

≥95%
Formula

C16H22N6O4
Formula Wt.

362.4
Synonym

TRH, Thyrotropin-releasing factor, TRF, Protirelin, Thyroliberin
Solubility

Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

T3100 MSDS PDF
Info Sheet

T3100 Info Sheet PDF

References

Fekete C, Lechan RM. Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. Endocr Rev. 2013 Dec 4:er20131087. [Epub ahead of print]. PMID: 24423980.

Pekary AE, Sattin A. Increased TRH and TRH-like peptide release in rat brain and peripheral tissues during proestrus/estrus. Peptides. 2013 Dec 1;52C:1-10. PMID: 24296042.

Daimon CM, Chirdon P, Maudsley S, et al. The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. Am J Alzheimers Dis (Columbia). 2013;1(1). PMID: 24199031.

Meier NT, Haslam IS, Pattwell DM, et al. Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin. PLoS One. 2013 Sep 2;8(9):e73596. PMID: 24023889.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S3313

    Sildenafil Citrate

    PDE5/6 inhibitor.

    ≥99%
  • C1600

    Carcinoembryonic Antigen (605-613)

    Carcinoembryonic antigen epitope.

    ≥95%
  • M3598

    Mizoribine Hydrobromide

    IMPDH inhibitor.

    ≥98%
  • V3378

    Vitamin B12

    Coenzyme, vitamin found in dairy, meat, eggs, f...

    ≥97%
  • E325125

    EIDD-2801

    COVID-19 research

    ≥98%
  • G5322

    GNF-5

    Abl inhibitor.

    ≥99%
  • M9367

    Myricetin

    Flavonol found in fruits and vegetables; COMT i...

    ≥98%
  • M5776

    Motilin, porcine

    Endogenous peptide hormone, involved in enteric...

    ≥98%
  • G4597

    18β-Glycyrrhetinic Acid

    Triterpene glycoside found in Glycyrrhiza; 15-H...

    ≥98%
  • M568262

    Mogrol

    Triterpenoid

    ≥99%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • T165133

    Tedizolid Phosphate

    Effective against gram-positive pathogens

    ≥98%
  • S1605

    Secretin, human

    Endogenous peptide hormone, involved in water h...

    ≥95%
  • S3352

    Sinefungin

    S-adenosylmethionine nucleoside analog; methylt...

    ≥95%
  • L960006

    LY-2606368

    CHK1 inhibitor.

    ≥98%
  • V7200

    VS-5584

    PI3K inhibitor.

    ≥98%
  • P1200

    PD-184352

    MEK1/2 and Raf inhibitor.

    ≥98%
  • N4974

    NMS-E628

    ALK and Ros1 inhibitor, Trk antagonist.

    ≥98%
  • R7680

    Recombinant M. Tuberculosis Antigen TB 38+6+10

    Tuberculosis antigen
  • R0105

    Rabeprazole Sodium

    H+/K+ ATPase and Scpc phosphatase inhibitor.

    ≥98%