LKT Labs

Biochemicals for Life Science Research

Thyrotropin-releasing Hormone

Thyrotropin-releasing Hormone

Product ID T3100
Cas No. 24305-27-9
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $82.00 In stock
10 mg $139.00 In stock
25 mg $245.00 In stock
Bulk Quote

Quicklinks

Description

Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide amide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and neuroprotective activities. TRH prevents oxidative stress, caspase-mediated apoptosis, glutamate toxicity, and neuroinflammation. Additionally, TRH stimulates epidermal regeneration in ex vivo models, activating would healing. TRH activates the TRH receptor.

Product Info

Cas No.

24305-27-9
Purity

≥95%
Formula

C16H22N6O4
Formula Wt.

362.4
Synonym

TRH, Thyrotropin-releasing factor, TRF, Protirelin, Thyroliberin
Solubility

Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

T3100 MSDS PDF
Info Sheet

T3100 Info Sheet PDF

References

Fekete C, Lechan RM. Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. Endocr Rev. 2013 Dec 4:er20131087. [Epub ahead of print]. PMID: 24423980.

Pekary AE, Sattin A. Increased TRH and TRH-like peptide release in rat brain and peripheral tissues during proestrus/estrus. Peptides. 2013 Dec 1;52C:1-10. PMID: 24296042.

Daimon CM, Chirdon P, Maudsley S, et al. The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. Am J Alzheimers Dis (Columbia). 2013;1(1). PMID: 24199031.

Meier NT, Haslam IS, Pattwell DM, et al. Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin. PLoS One. 2013 Sep 2;8(9):e73596. PMID: 24023889.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H9802

    Hyaluronic Acid Sodium (7-10 kDA)

    Glycosaminoglycan
  • S1810

    Secnidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • A1319

    Adenosine Triphosphate Disodium Hydrate

    Endogenous coenzyme, unit of cellular energy, r...

    ≥95%
  • S8251

    Sulfluramid

    Perfluorinated insecticide.

    ≥95%
  • K4401

    KL-1 Peptide

    Peptide, c-Kit ligand fragment.

    ≥95%
  • H965143

    Hydrolyzed Fumonisin B2

    Mycotoxin produced by Fusarium fungi that infec...

    ≥97% by ELSD
  • B1977

    Betulin

    Pentacyclic triterpene found in various plant s...

    ≥98%
  • F1607

    Febuxostat

    Xanthine oxidase inhibitor.

    ≥98%
  • D5868

    Doramapimod

    JNK, ALK, p38 MAPK inhibitor.

    ≥99%
  • D183734

    7-O-Desmethyl Rapamycin

    Rapamycin impurity

    ≥85%
  • A2046

    Aflatoxin B2

    Mycotoxin produced by species of Aspergillus; D...

    ≥98%
  • E4416

    Eledoisin

    Peptide, substance P analog; NK agonist.

    ≥95%
  • V5725

    Voglibose

    α-glucosidase inhibitor, potential GLP-1 agoni...

    ≥99%
  • B1652

    Benzo[a]pyrene

    Polycyclic aromatic hydrocarbon (PAH) found in ...

    ≥98%
  • A6268

    Aprotinin

    Polypeptide; serine protease inhibitor.

    ≥ 5400 u/mg
  • A2048

    Aflatoxin G1

    Mycotoxin produced by species of Aspergillus; D...

    ≥98%
  • P7359

    Psoralidin

    Phenol found in Psoralea coryfolia.

    ≥98%
  • L8008

    D-Luciferin, firefly, Free Acid

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • R3577

    Ritonavir

    HIV protease inhibitor.

    ≥98%
  • G4580

    Glucosamine Hydrochloride

    Endogenous amino sugar precursor required for p...

    ≥96%