LKT Labs

Biochemicals for Life Science Research

Thyrotropin-releasing Hormone

Thyrotropin-releasing Hormone

Product ID T3100
Cas No. 24305-27-9
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $82.00 In stock
10 mg $139.00 In stock
25 mg $245.00 In stock
Bulk Quote

Quicklinks

Description

Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide amide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and neuroprotective activities. TRH prevents oxidative stress, caspase-mediated apoptosis, glutamate toxicity, and neuroinflammation. Additionally, TRH stimulates epidermal regeneration in ex vivo models, activating would healing. TRH activates the TRH receptor.

Product Info

Cas No.

24305-27-9
Purity

≥95%
Formula

C16H22N6O4
Formula Wt.

362.4
Synonym

TRH, Thyrotropin-releasing factor, TRF, Protirelin, Thyroliberin
Solubility

Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

T3100 MSDS PDF
Info Sheet

T3100 Info Sheet PDF

References

Fekete C, Lechan RM. Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. Endocr Rev. 2013 Dec 4:er20131087. [Epub ahead of print]. PMID: 24423980.

Pekary AE, Sattin A. Increased TRH and TRH-like peptide release in rat brain and peripheral tissues during proestrus/estrus. Peptides. 2013 Dec 1;52C:1-10. PMID: 24296042.

Daimon CM, Chirdon P, Maudsley S, et al. The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. Am J Alzheimers Dis (Columbia). 2013;1(1). PMID: 24199031.

Meier NT, Haslam IS, Pattwell DM, et al. Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin. PLoS One. 2013 Sep 2;8(9):e73596. PMID: 24023889.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G4400

    Glabridin

    Isoflavonoid found in Glycyrrhiza; GABA-A posit...

    ≥98%
  • P3076

    PHT-427

    PDK1 and Akt inhibitor.

    ≥98%
  • D3353

    Diminazene Aceturate

    Diamidine; ACE2 activator, DNA polymerase inhib...

    ≥98%
  • A4944

    Amlexanox

    Azoxanthone derivative; S100A12 and S100A13 inh...

    ≥99%
  • T1852

    Tenovin-1

    SIRT1/2 inhibitor, indirect p53 activator.

    ≥98%
  • L3250

    D-Limonene

    Terpene found in the rind of various citrus fru...

    ≥97%
  • B1668

    Berteroin

    Thio sulforaphane analog, ITC.

    ≥97%
  • A7333

    Asiaticoside

    Triterpene found in Centella, prevents melanoge...

    ≥90%
  • S7618

    StemRegenin 1 Hydrochloride

    AhR antagonist.

    ≥98%
  • SC7056

    Snake venom – Crotalus durissus terrificus

    Snake venom found in Crotalus durrisus terrific...

    ≥98%
  • F5870

    N-formyl-Met-Leu-Phe

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • J5237

    JNJ-26854165

    MDM2 inhibitor.

    ≥98%
  • C9778

    Cytarabine

    Pyrimidine nucleoside (cytidine) analog; DNA ch...

    ≥98%
  • C0167

    Carbenoxolone

    Synthetic glycyrrhetinic acid derivative; 11β-...

    ≥98%
  • V3355

    Vindoline

    Semi-synthetic vinca alkaloid found in Catharan...

    ≥98%
  • N7332

    NSI-189

    Stem cell neurogenesis inducer.

    ≥99%
  • A0818

    15-Acetoxyscirpenol

    Trichothecene mycotoxin produced by Fusarium.

    ≥97%
  • A4926

    AMG-458

    c-MET inhibitor.

    ≥98%
  • R3222

    Rifamycin SV Monosodium

    Ansamycin; bacterial DNA-dependent RNA polymera...

    ≥98%
  • O4917

    Omeprazole

    H+/K+ ATPase inhibitor.

    ≥98%