• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Tobramycin Sulfate

Tobramycin Sulfate

Product ID T5605
Cas No. 79645-27-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $78.50 In stock
500 mg $270.60 In stock
1 g $375.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tobramycin is an aminoglycoside antibiotic that exhibits antibacterial and anti-inflammatory activities. Tobramycin prevents formation of the 70S bacterial ribosomal complex, inhibiting protein translation; it is highly effective in the treatment of Pseudomonas infections. In vitro, tobramycin inhibits T cell and neutrophil migration. In separate cellular models, this compound also decreases activation of NF-κB, expression of MUC5AC, and phosphorylation of ERK and p38 MAPK.

Product Info

Cas No.

79645-27-5

Purity

≥98%

Formula

(C18H37N5O9)2 • 5H2SO4

Formula Wt.

1425.45

Chemical Name

O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl- (1->4)]-2-deoxy-D-streptamine sulfate

IUPAC Name

4-amino-2-[4, 6-diamino-3-[3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2- hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol;sulfuric acid

Synonym

Gernebcin, Nebcin, Nebicina, Tobra, Tobradistin

Melting Point

287°C(dec.)

Solubility

Soluble in water (50 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T5605 MSDS PDF

Info Sheet

T5605 Info Sheet PDF

References

Papich MG. Antibiotic treatment of resistant infections in small animals. Vet Clin North Am Small Anim Pract. 2013 Sep;43(5):1091-107. PMID: 23890241.

Gziut M, MacGregor HJ, Nevell TG, et al. Anti-inflammatory effects of tobramycin and a copper-tobramycin complex with superoxide dismutase-like activity. Br J Pharmacol. 2013 Mar;168(5):1165-81. PMID: 23072509.

Nakamura S, Yanagihara K, Araki N, et al. High-dose tobramycin inhibits lipopolysaccharide-induced MUC5AC production in human lung epithelial cells. Eur J Pharmacol. 2011 Mar 21. [Epub ahead of print]. PMID: 21414310.

Periti P. Tobramycin--clinical pharmacology and chemotherapy. J Chemother. 1996 Jan;8 Suppl 1:3-30. PMID: 8948764.

King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D3362

    Dipyridamole

    PDE and adenosine deaminase inhibitor.

    ≥98%
  • A5035

    5-Aminosalicylic Acid

    Salicylic acid derivative; PPARγ agonist, pote...

    ≥98%
  • D0261

    Dapivirine

    RT inhibitor.

    ≥98%
  • T1004

    Paclitaxel Oxetane Ring-Opened 3-Acetyl 4-Benzoyl Impurity

    Synthesis impurity

    ≥92%
  • A3080

    AHU-377 Tris Salt

    LBQ657 prodrug; neprilysin inhibitor.

    ≥99%
  • A6932

    Aristolochic Acid A

    Found in Aristolochia and Radix; PLA2 inhibitor...

    ≥95%
  • T0098

    10-Deacetyltaxol C

    Diterpene found in Taxus; potential microtubule...

    ≥97%
  • R0105

    Rabeprazole Sodium

    H+/K+ ATPase and Scpc phosphatase inhibitor.

    ≥98%
  • M7530

    [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone

    Semi-synthetic peptide, melanocortin analog; MC...

    ≥98%
  • F5745

    Folic Acid

    Non-endogenous essential vitamin (B9), found in...

    ≥96%
  • B1640

    Benzydamine Hydrochloride

    NSAID; PG synthetase inhibitor.

    ≥98%
  • R2512

    RGD

    Tripeptide, binds cell surface integrins.

    ≥95%
  • O1177

    n-Octyl-3,4-Dimethylcaffeate

    Methylated derivative of n-octyl-caffeate.

    ≥98%
  • L186860

    Levomefolic acid calcium salt

    Folic acid derivative

    ≥98%
  • A822686

    Aureothricin

    Aureothricin is a member of the dithiolopyrrolo...

    ≥98%
  • A1319

    Adenosine Triphosphate Disodium Hydrate

    Endogenous coenzyme, unit of cellular energy, r...

    ≥95%
  • R4132

    RKI-1447

    ROCK1/2 inhibitor.

    ≥98%
  • C5773

    Cortistatin-14

    Endogenous neuropeptide, somatostatin analog; s...

    ≥95%
  • S1609

    Securinine

    Alkaloid found in Securinega; potential GABA-A ...

    ≥98%
  • B177550

    Benzbromarone

    Non-competitive inhibitor of xanthine oxidase.<...

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only