Description
Tosufloxacin is a fluoroquinolone antibiotic that exhibits antibacterial efficacy in ocular infections and against Mycoplasma. Tosufloxacin inhibits bacterial DNA gyrase and topoisomerase IV.
Tosufloxacin Tosylate
Product ID T5672
Cas No. 115964-29-9
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 115964-29-9 |
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| Purity | ≥98% |
| Formula | C19H15F3N4O3 • C7H8O3S |
| Formula Wt. | 576.55 |
| Chemical Name | 7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6- fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3- carboxylic acid toluenesulfonate |
| IUPAC Name | 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1, 8-naphthyridine-3-carboxylic acid;4-methylbenzenesulfonic acid |
| Synonym | Tosufloxacin toluenesulfonate, Ozex, Tosuxacin |
| Melting Point | 258-260°C |
| Solubility | Very slighlty soluble in water. |
| Appearance | Yellowish crystalline powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Akaike H, Miyashita N, Kubo M, et al. In vitro activities of 11 antimicrobial agents against macrolide-resistant Mycoplasma pneumoniae isolates from pediatric patients: results from a multicenter surveillance study. Jpn J Infect Dis. 2012;65(6):535-8. PMID: 23183207.
Ayaki M, Iwasawa A, Soda M, et al. Cytotoxicity of five fluoroquinolone and two nonsteroidal anti-inflammatory benzalkonium chloride-free ophthalmic solutions in four corneoconjunctival cell lines. Clin Ophthalmol. 2010 Sep 20;4:1019-24. PMID: 20922036.
Tanaka M, Onodera Y, Uchida Y, et al. Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus. Antimicrob Agents Chemother. 1997 Nov;41(11):2362-6. PMID: 9371334.