• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ulixertinib

Ulixertinib

Product ID U451349
Cas No. 869886-67-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $150.40 In stock
25 mg $263.00 In stock
100 mg $901.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ulixertinib is an ERK1/2 inhibitor that has been found to impair proliferation, arrest cell cycle, and induce apoptosis in lymphoma cell lines. Ulixertinib has also demonstrated effectiveness in several models that show either intrinsic or acquired resistance to MAPK pathway inhibitors.

Product Info

Cas No.

869886-67-9

Purity

≥98%

Formula

C21H22Cl2N4O2

Formula Wt.

433.33

IUPAC Name

N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-[5-chloro-2-(propan-2-ylamino)pyridin-4-yl]-1H-pyrrole-2-carboxamide

Synonym

BVD-523, VRT752271

Solubility

DMSO:86 mg/mL (198.46 mM) Ethanol:15 mg/mL (34.61 mM) Water:Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

U451349 MSDS PDF

Info Sheet

U451349 Info Sheet PDF

References

Ding WJ, Tao WP, Zeng T, et al. Selective ERK inhibitor ulixertinib inhibits proliferation and induces apoptosis in lymphoma cell lines. Int J Clin Exp Med. 2017;9(6):10955-10962.

Germann U, Furey B, Roix J, et al. The selective ERK inhibitor BVD-523 is active in models of MAPK pathway-dependent cancers, including those with intrinsic and acquired drug resistance. Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G0180

    Gastrin I, human

    Endogenous peptide hormone involved in feeding ...

    ≥98%
  • V344761

    Vitamin K2

    2-methyl-1,4-naphthoquinone derivative

    ≥98%
  • S0930

    Schisantherin A

    Dibenzocyclooctadiene found in Schisandra.

    ≥98%
  • C2949

    Chlorpheniramine Maleate

    Alkylamine; histamine H1 antagonist, SERT and N...

    ≥98%
  • V5725

    Voglibose

    α-glucosidase inhibitor, potential GLP-1 agoni...

    ≥99%
  • T3035

    Thienylheptyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥95%
  • O4672

    Olsalazine Sodium

    5-Aminosalicylate prodrug, NSAID; COX-1/2 inhib...

    ≥98%
  • B8278

    Butoconazole Nitrate

    Imidazole; 14-α demethylase inhibitor.

    ≥98%
  • C2847

    Chlormadinone Acetate

    Synthetic steroid hormone; AR and ER antagonist...

    ≥96%
  • S336486

    Simeprevir

    NS3/4A inhibitor

    ≥99%
  • R3584

    Rivaroxaban

    Oxazolidone derivative; Factor Xa inhibitor.

    ≥98%
  • F8272

    Fusarenon X

    Trichothecene mycotoxin produced by Fusarium.

    ≥98%
  • A464768

    Altertoxin 1

    Mycotoxin contaminant in food and feed.

    ≥97%
  • P7056

    Procaterol Hydrochloride

    β2-adrenergic agonist.

    ≥98%
  • C5782

    Coumarin

    Benzopyrone found in various plants, precursor ...

    ≥98%
  • L8010

    D-Luciferin Potassium

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • S8007

    Substance P (1-7)

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • H9862

    Hypothemycin

    Polyketide found in Setophoma.

    ≥96%
  • P6954

    Pioglitazone Hydrochloride

    Thiazolidinedione; PPARα/γ agonist, mitoNEET ...

    ≥98%
  • L960012

    LY-3214996

    ERK1/2 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only