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Virginiamycin M1

Virginiamycin M1

Product ID V3325
Cas No. 21411-53-0
Purity ≥97%
Product Unit SizeCostQuantityStock
1 mg $36.80 In stock
5 mg $47.30 In stock
50 mg $157.50 In stock
250 mg $315.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Virginiamycin M1 is a macrolide antibiotic commonly used in livestock as a growth promoter; it is also occasionally used to prevent microbial contamination in ethanol fuels. Virginiamycin M1 is an antibacterial that binds 23S rRNA of the bacterial 50S ribosome, inhibiting peptidyl transferase activity. This compound displays insecticidal activity against Leptinotarsa and acaricidal activity against Tetranychus.

Product Info

Cas No.

21411-53-0

Purity

≥97%

Formula

C28H35N3O7

Formula Wt.

525.59

IUPAC Name

(10R,11R,12E,17E,19E,21S)-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone

Synonym

Mikamycin A, Staphilomycin, Ostreogrycin A, Virginiamycin M1, Pristinamycin IIA

Melting Point

165-170°C

Solubility

Soluble in ethanol (3-4%) , methanol (3-4%), DMSO, Dichloromethane, DMF, and sparingly, in water.

Appearance

Slightly yellow powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

V3325 MSDS PDF

Info Sheet

V3325 Info Sheet PDF

References

Batista L, Rivera M, Fonseca M, et al. The influence of virginiamycin on digestion and ruminal parameters under feedlot conditions. Transl Anim Sci. 2024 Feb 14:8:txae019. PMID: 38406320.

Compart DM, Carlson AM, Crawford GI, et al. Presence and biological activity of antibiotics used in fuel ethanol and corn co-product production. J Anim Sci. 2013 May;91(5):2395-404. PMID: 23463564.

Qiu Y, Yang F, Liu Z, et al. Determination of virginiamycin M1 and S1 residues in livestock and poultry products by liquid chromatography-tandem mass spectrometry. Se Pu. 2012 May;30(5):463-7. PMID: 22934408.

Champney WS, Tober CL. Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr Microbiol. 2000 Aug;41(2):126-35. PMID: 10856379.

Prikrylová V, Samoukina GV, Kandybin NV, et al. Pesticidal activity of virginiamycins S1 and M1. Folia Microbiol (Praha). 1992;37(5):386-8. PMID: 1493906.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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