Description
WS3 is an activator of islet β cell proliferation that may display anti-diabetic activity. WS3 also promotes retinal pigment epithelial cell proliferation and is under examination as a potential treatment for macular degeneration.
WS3
Product ID W7200
Cas No. 1421227-52-2
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 1421227-52-2 |
|---|---|
| Purity | ≥98% |
| Formula | C28H30F3N7O3 |
| Formula Wt. | 569.59 |
| Chemical Name | N-(6-(4-(3-(4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide |
| IUPAC Name | N-(6-{4-[({4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}carbamoyl)amino]phenoxy}-4-pyrimidinyl)cyclopropanecarboxamide |
| Solubility | DMSO 100 mg/mL Ethanol 80 mg/mL Water Insoluble |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Swoboda JG, Elliott J, Deshmukh V, et al. Small molecule mediated proliferation of primary retinal pigment epithelial cells. ACS Chem Biol. 2013 Jul 19;8(7):1407-11. PMID: 23621521.
Shen W, Tremblay MS, Deshmukh VA, et al. Small-molecule inducer of β cell proliferation identified by high-throughput screening. J Am Chem Soc. 2013 Feb 6;135(5):1669-72. Erratum in: J Am Chem Soc. 2013 Mar 20;135(11):4573. PMID: 23330637.