LKT Labs

Biochemicals for Life Science Research

Ziprasidone

Ziprasidone

Product ID Z3463
Cas No. 146939-27-7
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $54.60 In stock
500 mg $126.50 In stock
1 g $202.70 In stock
5 g $817.30 In stock
Bulk Quote

Quicklinks

Description

Ziprasidone is an atypical antipsychotic that acts as an antagonist at D2 receptors and 5-HT1D receptors and as an agonist at 5-HT1A receptors; this binding profile allows it to exhibit antipsychotic, antidepressant, and anxiolytic benefits. Ziprasidone is clinically used to treat bipolar disorder, schizophrenia, and sleeplessness/insomnia in individuals with psychosis. In a clinical setting, ziprasidone improved latency to REM, duration of slow wave sleep, total sleep time, and sleep efficiency.

Product Info

Cas No.

146939-27-7
Purity

≥98%
Formula

C21H21ClN4OS
Formula Wt.

412.94
Chemical Name

2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1- piperazinyl)ethyl)-6-chloro-1,3-dihydro-

IUPAC Name

5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1, 3-dihydroindol-2-one
Synonym

Geodon, Zeldox, CP-88059
Melting Point

213-215°C
Appearance

Pale brown powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

Z3463 MSDS PDF
Info Sheet

Z3463 Info Sheet PDF

References

Takeuchi H, Suzuki T, Bies RR, et al. Estimated dopamine D2 receptor occupancy from plasma concentrations of atypical antipsychotics and subjective experience/drug attitude in schizophrenia: an analysis of the CATIE data. Schizophr Res. 2013 Nov;150(2-3):373-9. PMID: 24028745.

Findling RL, Cavuş I, Pappadopulos E, et al. Efficacy, long-term safety, and tolerability of ziprasidone in children and adolescents with bipolar disorder. J Child Adolesc Psychopharmacol. 2013 Oct;23(8):545-57. PMID: 24111980.

Baskaran A, Summers D, Willing SL, et al. Sleep architecture in ziprasidone-treated bipolar depression: a pilot study. Ther Adv Psychopharmacol. 2013 Jun;3(3):139-49. PMID: 24167686.

Farah A. Atypicality of atypical antipsychotics. Prim Care Companion J Clin Psychiatry. 2005;7(6):268-74. PMID: 16498489.

Stimmel GL, Gutierrez MA, Lee V. Ziprasidone: an atypical antipsychotic drug for the treatment of schizophrenia. Clin Ther. 2002 Jan;24(1):21-37. PMID: 11833834.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T0120

    2′,7-bis(triethylsilyl)taxol

    Synthesis intermediate

    ≥98%
  • G1652

    Genistein

    Phytoestrogen, isoflavone found in various plan...

    ≥98%
  • S8014

    Substance P, Free Acid

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • P6801

    Pravastatin Sodium

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • D5611

    Docosahexaenoic Acid (all cis-4,7,10,13,16,19) Methyl Ester

    Essential fatty acid found in fish oil, involve...

    ≥99%
  • P4008

    PKC412

    Staurosporine derivative; PKC and FLT3 inhibito...

    ≥98%
  • G0044

    Galantide

    Peptide; galanin antagonist.

    ≥95%
  • R0243

    Raloxifene Hydrochloride

    SERM.

    ≥98%
  • P0297

    Paroxetine Hydrochloride Hemihydrate

    FIASMA, SERT and NET inhibitor, mAChR antagonis...

    ≥98%
  • G3358

    Ginkgolide ABC

    Mixture of Ginkgolides A, B and C, found in Gin...

    ≥98%
  • C5863

    Coptisine Chloride, natural

    Isoquinoline alkaloid found in a variety of pla...

    ≥98%
  • R1876

    all-trans-Retinol

    Diterpene component of vitamin A, differentiati...

    ≥95%
  • C9610

    D-Cycloserine

    NMDA partial agonist, D-Ala-D-Ala ligase inhibi...

    ≥98%
  • L0350

    Lamivudine

    Nucleoside (thymidine) analog; RT inhibitor.

    ≥99%
  • P3540

    PIK-75 Hydrochloride

    p110α PI3K inhibitor.

    ≥98%
  • M5853

    Moniliformin sodium salt

    Mycotoxin produced by species of Fusarium; pote...

    ≥98%
  • O9397

    Oxytetracycline Hydrochloride

    Tetracycline; protein translation inhibitor.

    ≥96%
  • S771339

    STING Agonist-12

    STING activator

    ≥99%
  • R4132

    RKI-1447

    ROCK1/2 inhibitor.

    ≥98%
  • T4800

    TM3-0089 Sodium Monohydrate

    CRTH2 inhibitor.

    ≥98%