• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
β-Endorphin, human

β-Endorphin, human

Product ID E5217
Cas No. 61214-51-5
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $245.30 Please Inquire
2 mg $417.10 In stock
5 mg $735.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

β-Endorphin is an endogenous opioid peptide that acts as an agonist at μ-opioid receptors (μORs) and exhibits immunomodulatory, neuromodulatory, antidepressant, and antinociceptive/analgesic activities. In vivo, β-endorphin increases levels of B-cells and production of antibodies as well as secretion of IL-4 and proliferation of spleenocytes, shifting the immune response toward Th2-specific mediators. This peptide, like other endogenous opioids, plays a significant role in reward and reinforcement signaling, especially in brain regions such as the ventral tegmental area (VTA) and nucleus accumbens (NAcc). β-Endorphin release is induced during exercise and shows antidepressant activity in clinical studies.

Product Info

Cas No.

61214-51-5

Purity

≥95%

Formula

C158H251N39O46S

Formula Wt.

3465.06

Synonym

β-Lipotropin (61-91), human; β-Lipotropin C-fragment; LPH (61-91).

Solubility

Soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E5217 MSDS PDF

Info Sheet

E5217 Info Sheet PDF

References

Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • V1769

    Verapamil Hydrochloride

    L-type Ca2+ channel blocker.

    ≥98%
  • F285081

    Fidaxomicin

    Macrocycle

    ≥98%
  • F4420

    Boc-FLFLF

    Peptide; FRP1 antagonist.

    ≥95%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • T1024

    Baccatin VI

    Fermentation impurity

    ≥98%
  • T1777

    S,S-(+)-Tetrandrine

    Benzylisoquinoline alkaloid originally found in...

    ≥98%
  • E6396

    EPZ005687

    EZH2 HMT inhibitor.

    ≥99%
  • G4597

    18β-Glycyrrhetinic Acid

    Triterpene glycoside found in Glycyrrhiza; 15-H...

    ≥98%
  • A7071

    Atriopeptin II, rat/rabbit/mouse

    ANP analog, cardiomodulatory peptide; NPR-A ago...

    ≥95%
  • P0245

    Palmatine Chloride Hydrate

    Isoquinoline alkaloid found in Corydalis, Phell...

    ≥96%
  • A5134

    Aminophylline Anhydrous

    Adenosine antagonist, PDE inhibitor.

    ≥98%
  • C1633

    Cefotaxime Sodium

    β-lactam cephalosporin; penicillin binding pro...

    ≥96%
  • D3214

    2′,3′-Dideoxyinosine

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • T3585

    Tivozanib

    VEGFR1/2/3, c-Kit, PDGFR inhibitor.

    ≥98%
  • G1658

    Gentamycin Sulfate

    Aminoglycoside; protein translation inhibitor.<...

  • M5675

    Motilin, canine

    Endogenous peptide hormone; motilin agonist.

    ≥95%
  • O1178

    n-Octyl-3-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • T7232

    S-Trityl-L-cysteine

    Organosulfur found in garlic; kinesin Eg5 inhib...

    ≥98%
  • S5869

    Sorafenib Tosylate

    c-Raf, RET, VEGFR1 inhibitor, potential HMT inh...

    ≥99%
  • R5992

    Roxithromycin

    Macrolide; protein synthesis inhibitor.

    ≥96%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only