• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
(−)-Epigallocatechin

(−)-Epigallocatechin

Product ID E6233
Cas No. 970-74-1
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $48.30 In stock
5 mg $173.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

(-)-Epigallocatechin (EGC) is a flavanol/catechin originally found in Camilla and other plant sources; it exhibits antioxidative, neuromodulatory, antithrombotic/anticoagulant, anticancer, anti-metastatic, and anti-osteoporotic activities. EGC displays agonist activity at cannabinoid 1 (CB1) receptors. In vivo, EGC inhibits platelet aggregation and increases activated partial thromboplastin time. Additionally, EGC inhibits expression of FLT3 and decreases phosphorylation of p38 MAPK, Akt, and STAT5 in acute myelogenous leukemia (AML) cells, suppressing cell proliferation. In breast cancer cells, EGC inhibits cell migration and invasion. This compound also decreases adipocyte formation, suppresses expression of PPARγ, CEBP, and FABP4, and increases osteogenic differentiation in vitro.

Product Info

Cas No.

970-74-1

Purity

≥98%

Formula

C15H14O7

Formula Wt.

306.27

IUPAC Name

(2R,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

Synonym

(-)-3,3',4',5,5',7-Flavanhexol, Epigallocatechin, Epigallocatechol

Melting Point

208-210°C

Solubility

Soluble in water or alcohol.

Appearance

White Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

E6233 MSDS PDF

Info Sheet

E6233 Info Sheet PDF

Brochures

Green Tea Flyer

Brochures

Natural Products Booklet

References

Chen XQ, Wang XB, Guan RF, et al. Blood anticoagulation and antiplatelet activity of green tea (-)-epigallocatechin (EGC) in mice. Food Funct. 2013 Oct;4(10):1521-5. PMID: 24056410.

Ly BT, Chi HT, Yamagishi M, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One. 2013 Jun 20;8(6):e66378. PMID: 23840454.

Ko CH, Siu WS, Wong HL, et al. Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro. J Agric Food Chem. 2011 Sep 28;59(18):9870-6. PMID: 21877759.

Korte G, Dreiseitel A, Schreier P, et al. Tea catechins' affinity for human cannabinoid receptors. Phytomedicine. 2010 Jan;17(1):19-22. PMID: 19897346.

Kushima Y, Iida K, Nagaoka Y, et al. Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line. Biol Pharm Bull. 2009 May;32(5):899-904. PMID: 19420761.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G4799

    Glycitin

    Glycosylated isoflavone found in soy; TAS2R ago...

    ≥98%
  • A0963

    Adrenocorticotropic Hormone (1-10), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • G346851

    Givinostat Hydrochloride

    Non-selective HDAC inhibitor.

    ≥98%
  • L9600

    LY-2090314

    GSK-3 inhibitor.

    ≥98%
  • S5722

    Sofosbuvir

    Viral RNA polymerase inhibitor.

    ≥98%
  • C1718

    Cepharanthine, 95%

    Alkaloid found in Stephania.

    ≥95%
  • F6803

    FRAX486

    PAK inhibitor.Smo inhibitor.

    ≥98%
  • O7053

    L-Ornithine Hydrochloride

    Non-proteinogenic amino acid, L-arginine metabo...

    ≥98%
  • P2002

    PF-04691502 Dihydrate

    PI3K and mTOR inhibitor.

    ≥98%
  • S1604

    Secretin Acetate

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • R3374

    Risedronic Acid

    Bisphosphonate; inhibits transfer of farnesyl p...

    ≥97%
  • A6823

    Argatroban

    Thrombin inhibitor.

    ≥98%
  • L1869

    Lercanidipine Hydrochloride

    Calcium channel blocker.

    ≥98%
  • O0977

    Octopamine Hydrochloride

    Endogenous biogenic amine, norepinephrine-like ...

    ≥98%
  • N344786

    N-Nitroso Valsartan Methyl Ester

    Valsartan impurity

  • A6827

    Argipressin Acetate

    Endogenous peptide, involved in vascular contra...

    ≥95%
  • L8008

    D-Luciferin, firefly, Free Acid

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • C0267

    Carnosol

    Diterpene compound originally found in Rosmarin...

    ≥98%
  • A5031

    4-Aminophenylphosphate Disodium

    Alkaline phosphatase substrate used to quantify...

    ≥98%
  • P0219

    Paeonol

    Found in Paeonia, Arisaema, Dioscorea; MAO-A/B ...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only