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Carbimazole

Carbimazole

Product ID C0172
Cas No. 22232-54-8
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $48.10 In stock
1 g $69.60 In stock
5 g $187.80 In stock
10 g $347.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Carbimazole is a methimazole prodrug that is clinically used to treat hyperthyroidism and Graves’ disease; it exhibits immunomodulatory and anti-thyroid activities. Carbimazole inhibits thyroid peroxidase, decreasing production of thyroid hormones T3 and T4. In clinical subjects with Graves’ disease, carbimazole increases levels of IL-2 and free radical scavengers and decreases levels of IL-2Rs.

Product Info

Cas No.

22232-54-8

Purity

≥98%

Formula

C7H10N2O2S

Formula Wt.

186.23

Chemical Name

2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1- carboxylic acid ethyl ester

IUPAC Name

ethyl 3-methyl-2-sulfanylideneimidazole-1-carboxylate

Synonym

Athyromazole, Neo-mercazole, Neo-Thyreostat

Melting Point

122-125°C

Solubility

Soluble in water (500parts), ethanol (50parts), and chloroform (3parts).

Appearance

White-almost white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C0172 MSDS PDF

Info Sheet

C0172 Info Sheet PDF

References

Manna D, Roy G, Mugesh G. Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action. Acc Chem Res. 2013 Nov 19;46(11):2706-15. PMID: 23883148.

Wilson R, McKillop JH, Buchanan LM, et al. The effect of carbimazole therapy on interleukin 2, interleukin 2 receptors and free radicals. Autoimmunity. 1990;8(1):3-7. PMID: 2129783.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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