Description
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
Product Unit Size | Cost | Quantity | Stock |
---|
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
Cas No. | 113276-94-1 |
---|---|
Purity | ≥98% |
Formula | C12H15N3O2S 2HC1 |
Formula Wt. | 338.25 |
Chemical Name | N-(2-(methylamino)ethyl)- dihydrochloride 5-Isoquinolinesulfonamide |
IUPAC Name | N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide;dihydrochloride |
Synonym | H8 dihydrochloride salt |
Appearance | White to off white powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Sui HY, Luan HY, Liu YJ. Involvement of protein kinase A activation and phospholipase A(2) inhibition in the adenosine-activated basolateral 50 pS K(+) channels in the thick ascending limb of the rat kidney. Sheng Li Xue Bao. 2012 Aug 25;64(4):449-54. PMID: 22907306.
Hou L, Wang X. PKC and PKA, but not PKG mediate LPS-induced CGRP release and [Ca(2+)](i) elevation in DRG neurons of neonatal rats. J Neurosci Res. 2001 Nov 15;66(4):592-600. PMID: 11746379.
Ornithine decarboxylase inhibitor.
β1-adrenergic agonist, β2- and α1-adrenergic...
Endogenous peptide; FPRL1/2 agonist.
Endogenous antimicrobial peptide, binds bacteri...
Benzophenanthridine alkaloid found in Garcinia....
Saponin found in Dioscorea; Na+/K+ ATPase and C...
Diarylether; bacterial ENR binder, fatty acid s...
Endogenous tachykinin peptide, involved in infl...
5-HT2A antagonist, potential α1-adrenergic ant...
5-HT1A partial agonist, 5-HT2, histamine, α1/2...
L-type and T-type Ca2+ and TRP antagonist.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
ATP-sensitive K+ channel activator, α-adrenerg...
Purine nucleoside analog; DNA chain terminator,...
Polyphenol found in various plant sources, resv...
Organosulfide found in Allium; cholesterol synt...
Neuraminidase inhibitor.
D2/3 agonist.
Folate source co-administered with methotrexate...
Steroid; glucocorticoid agonist.