LKT Labs

Biochemicals for Life Science Research

Neuromedin B, pig

Neuromedin B, pig

Product ID N1980
Cas No. 87096-84-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $131.00 In stock
2 mg $223.00 In stock
5 mg $392.00 In stock
Bulk Quote

Quicklinks

Description

Neuromedin B is an endogenous bombesin-related peptide that binds BB receptors, displaying the greatest affinity for the BB1 receptor. Neuromedin B exhibits anorexigenic and cardiomodulatory activities, decreasing food intake, inducing bradycardia, and slowing gastric emptying in vivo. Neuromedin B also activates ERK1/2 signaling, increasing osteoblast proliferation and bone formation. Additionally, neuromedin B increases secretion of luteinizing hormone (LH) and gonadotropin-releasing hormone (GnRH) in vitro and in vivo.

Product Info

Cas No.

87096-84-2
Purity

≥95%
Formula

C52H73N15O12S
Formula Wt.

1132.3
Chemical Name

1-glycine-2-L-asparagine-3-L-leucine-4-de-L- glutamine-7-L-threonine-Ranatensin
IUPAC Name

(2S)-2-[(2-aminoacetyl)amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S, 3R)-1-[[2-[[(2S)-1-[[1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl] amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1- oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino] -1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4- methyl-1-oxopentan-2-yl]butanediamide
Solubility

Soluble in water (1 mg/mL).
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

N1980 MSDS PDF
Info Sheet

N1980 Info Sheet PDF

References

Boughton CK, Patel SA, Thompson EL, et al. Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats. Regul Pept. 2013 Nov 10;187:6-11. PMID: 24120470.

Saito H, Nakamachi T, Inoue K, et al. Autocrine effects of neuromedin B stimulate the proliferation of rat primary osteoblasts. J Endocrinol. 2013 Apr 15;217(2):141-50. PMID: 23428580.

Sayegh AI. The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:343-70. PMID: 23317790.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C324091

    Ciclesonide

    Corticosteroid

    ≥98%
  • R3220

    Rifampicin

    Ansamycin; bacterial DNA-dependent RNA polymera...

    ≥98%
  • P7000

    PR-619

    Deubiquitinating enzyme inhibitor.

    ≥98%
  • E7556

    Etodolac

    NSAID; TRPA1 agonist, COX-2 inhibitor.

    ≥98%
  • F3354

    Finasteride

    Steroid 5-α-reductase inhibitor.

    ≥98%
  • T3454

    Tinidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • G733404

    GSK3685032

    Reversible DNMT1-selective inhibitor

    ≥98%
  • A4440

    Allicin

    Organosulfur found in garlic, binds DNA; inward...

    ≥98%
  • T9974

    [Asp371]-Tyrosinase (369-377), human

    Proteasome antigen.

    ≥95%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • K624760

    KPT-276

    CRM1/XPO1 inhibitor.

    ≥99%
  • T7056

    Troglitazone

    Thiazolidinedione; PPARγ agonist, ATP-sensitiv...

    ≥97%
  • T2402

    TG100-115

    p110δ and p110γ PI3K inhibitor.

    ≥98%
  • R3011

    Recombinant TpN 15 protein

    Recombinant protein containing Treponema pallid...

    ≥95%
  • C2969

    Chromomycin A3

    Anthraquinone, Mg2+/Zn2+ chelator; bacterial DN...

    ≥97%
  • O4917

    Omeprazole

    H+/K+ ATPase inhibitor.

    ≥98%
  • A5059

    Amoxapine

    5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenerg...

    ≥98%
  • P1869

    Perindopril Erbumine

    ACE inhibitor.

    ≥95%
  • V014463

    Valsartan Methyl Ester

    Valsartan impurity

    ≥98%
  • L8011

    D-Luciferin Sodium

    Heterocyclic light-emitting compound, natural l...

    ≥99%