Description
Vatalanib is an inhibitor of VEGFR1/2/3. It decreases tumor growth in models of human glioma when administered with HET0016, a 20-HETE synthesis inhibitor.
Product Unit Size | Cost | Quantity | Stock |
---|
Vatalanib is an inhibitor of VEGFR1/2/3. It decreases tumor growth in models of human glioma when administered with HET0016, a 20-HETE synthesis inhibitor.
Cas No. | 212141-54-3 |
---|---|
Purity | ≥98% |
Formula | C20H15ClN4 |
Formula Wt. | 346.82 |
Chemical Name | Vatalanib |
IUPAC Name | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine |
Synonym | PTK-787, PTK 787, PTK787, ZK-222584, ZK 222584, ZK222584, CGP-797870, ZK232934 |
Solubility | Solubility in DMSO - ~100 mg/mL. |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Shankar A., Borin T., et al. Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma. Onco Target Ther. 9:1204-19 (2016). PMID: 27022280.
Found in Salvia; MAG lipase inhibitor.
Polyether neurotoxin found in Karenia brevis; N...
AR antagonist.
Diterpene found in Rosmarinus.
Sulfonylurea; SUR1 antagonist.
H+/K+ ATPase inhibitor.
PDGFR and c-Kit inhibitor.
Semi-synthetic vinca alkaloid found in Catharan...
Aza-anthracenedione, DNA intercalator; topoisom...
p110δ PI3K inhibitor.
Bcl-2, Bcl-xl, sialyl transferase inhibitor.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
For use in amino acid analysis.
Coumarin lactone found in chicory and other pla...
NSAID; COX-1/2 inhibitor.
Penicillin derivative, chelating agent; carboxy...
Peptide, GnRH analog; GnRH agonist.
Triterpene sapogenin found in species of Panax;...
Triterpene saponin found in species of Panax.
Endogenous neuropeptide hormone, involved in so...