LKT Labs

Biochemicals for Life Science Research

Escitalopram Oxalate

Escitalopram Oxalate

Product ID E7209
Cas No. 219861-08-2
Purity ≥99%
Product Unit SizeCostQuantityStock
10 mg $71.50 In stock
50 mg $183.60 In stock
100 mg $306.20 In stock
Bulk Quote

Quicklinks

Description

Escitalopram is the S-enantiomer of racemic citalopram; like citalopram, this compound is an SSRI that exhibits antidepressant and anxiolytic qualities and is also effective in treating OCD. Escitalopram inhibits the serotonin transporter (SERT), preventing reuptake of serotonin. Escitalopram may have other potential uses, as it decreased weight in a study of obese subjects with binge eating disorder and displayed anti-inflammatory activity through inhibition of NO and TNF-α production. This compound is associated with prolongation of the cardiac QT interval and may inhibit osteoblast and osteoclast formation as well.

Product Info

Cas No.

219861-08-2
Purity

≥99%
Formula

C22H21FN2O • C2H2O4

Formula Wt.

414.43
IUPAC Name

(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5- carbonitrile;oxalic acid
Melting Point

152-153°C
Solubility

freely soluble in methanol and dimethyl sulfoxide (DMSO), soluble in isotonic saline solution, sparingly soluble in water and ethanol, slightly soluble in ethyl acetate, and insoluble in heptane.
Appearance

White powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

E7209 MSDS PDF
Info Sheet

E7209 Info Sheet PDF

References

Hodge JM, Wang Y, Berk M, et al. Selective serotonin reuptake inhibitors inhibit human osteoclast and osteoblast formation and function. Biol Psychiatry. 2013 Jul 1;74(1):32-9. PMID: 23260229.

Tynan RJ, Weidenhofer J, Hinwood M, et al. A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia. Brain Behav Immun. 2012 Mar;26(3):469-79. PMID: 22251606.

Zhong H, Haddjeri N, Sánchez C. Escitalopram, an antidepressant with an allosteric effect at the serotonin transporter--a review of current understanding of its mechanism of action. Psychopharmacology (Berl). 2012 Jan;219(1):1-13. PMID: 21901317.

van Gorp F, Whyte IM, Isbister GK. Clinical and ECG effects of escitalopram overdose. Ann Emerg Med. 2009 Sep;54(3):404-8. PMID: 19556032.

Stein DJ, Andersen EW, Tonnoir B, et al. Escitalopram in obsessive-compulsive disorder: a randomized, placebo-controlled, paroxetine-referenced, fixed-dose, 24-week study. Curr Med Res Opin. 2007 Apr;23(4):701-11. PMID: 17407626.

Kasper S, Stein DJ, Loft H, et al. Escitalopram in the treatment of social anxiety disorder: randomised, placebo-controlled, flexible-dosage study. Br J Psychiatry. 2005 Mar;186:222-6. PMID: 15738503.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T6833

    Triacetyl Aloe-emodin (Impurity A)

    Derivative of aloe-emodin, anthraquinone found ...

    ≥98%
  • E6814

    Erdosteine

    Thiol derivative, antioxidant.

    ≥98%
  • N3213

    Nidulal

    Sesquiterpene found in Nidula.

    ≥95%
  • K740640

    KSQ-4279

    USP1 inhibitor

    ≥98%
  • F1655

    Fenoprofen Calcium Dihydrate

    NSAID; COX-1/2 inhibitor.

    ≥97%
  • T3100

    Thyrotropin-releasing Hormone

    Endogenous tripeptide, involved in HPA signalin...

    ≥95%
  • G7232

    GS-9973

    Syk inhibitor.

    ≥98%
  • N7208

    NSC-74859

    STAT3 inhibitor.

    ≥98%
  • E2003

    Efavirenz

    Non-nucleoside RT inhibitor.

    ≥99%
  • D183745

    Destruxin B

    Cyclic depsipeptide is a secondary metabolite i...

    ≥96%
  • S771337

    STING Agonist-1

    Indirect activator of STING signaling

    ≥98%
  • C0824

    CCG1423

    Serum response factor inhibitor and MRTF-A bind...

    ≥98%
  • A4930

    7-Aminoactinomycin D

    Actinomycin derivative used to study apoptosis ...

    ≥98%
  • C1878

    Cetrimide

    Mixture of quaternary ammonium salts, cationic ...

    ≥98%
  • P1764

    Pep-1 Peptide

    Cell-penetrating peptide, carries large conjuga...

    ≥95%
  • F4432

    FLI-06

    Notch inhibitor.

    ≥99%
  • Z0252

    Zanamivir

    Neuraminidase inhibitor.

    ≥98%
  • U6856

    Urocortin II, human

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • F5766

    Forchlorfenuron

    Synthetic cytokinin, plant growth regulator; fi...

    ≥98%
  • N3496

    Nizatidine

    Histamine H2 inverse agonist.

    ≥98%