Description
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
Product Unit Size | Cost | Quantity | Stock |
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JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
Cas No. | 3520-43-2 |
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Purity | ≥90% |
Formula | C25H27Cl4IN4 |
Formula Wt. | 652.23 |
Chemical Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
IUPAC Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
Solubility | Soluble in methanol, DMSO. |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Zhang C, Tian Y, Song F, et al. Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep. 2015 Sep 8. [Epub ahead of print]. PMID: 26352531.
Jiang Z, Li X, Lin Z, et al. Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis. Int J Clin Exp Pathol. 2015 Jul 1;8(7):7774-85. PMID: 26339342.
Smiley ST, Reers M, Mottola-Hartshorn C, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3671-5. PMID: 2023917.
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