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β-Carotene

β-Carotene

Product ID C0269
Cas No. 7235-40-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $30.70 In stock
5 g $61.10 In stock
25 g $204.30 In stock
50 g $347.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

β-Carotene is a red-orange terpene pigment originally found in various plants and fruits; it is a prodrug for vitamin A. It exhibits antioxidative, cytoprotective, anticancer, anti-inflammatory, anti-hyperlipidemic, and anti-obesity activities. β-Carotene is used in research models to quantify antioxidative activity. In bone marrow cells, it protects against radioactive isotope-induced DNA damage. In breast cancer cells, this compound induces cell cycle arrest and apoptosis, decreasing cellular viability. It decreases total cholesterol, VLDL and LDL levels, suppresses expression of SREBP2 and LDL-R, and increases expression of PPARα in vivo. In other animal models, this compound decreases body fat and adipocyte size and suppresses TNF-α-induced inflammation.

Product Info

Cas No.

7235-40-7

Purity

≥98%

Formula

C40H56

Formula Wt.

536.87

Chemical Name

β,β-Carotene

IUPAC Name

1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12, 16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11, 13,15,17-nonaenyl]cyclohexene

Synonym

Carotaben, Provatene, Solatene

Melting Point

183°C

Solubility

Insoluble in water. Sparingly soluble in ethanol. Soluble in benzene or chloroform.

Appearance

Dark Yellowish Red Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C0269 MSDS PDF

Info Sheet

C0269 Info Sheet PDF

References

Abdel-Mageed WM, Bayoumi SA, Salama AA, et al. Antioxidant lipoxygenase inhibitors from the leaf extracts of Simmondsia chinensis. Asian Pac J Trop Med. 2014 Sep;7S1:S521-6. PMID: 25312177.

Berti AP, Düsman E, Mariucci RG, et al. Antimutagenic and radioprotective activities of beta-carotene against the biological effects of iodine-131 radiopharmaceutical in Wistar rats. Genet Mol Res. 2014 Mar 31;13(1):2248-58. PMID: 24737473.

Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385.

Silva LS, de Miranda AM, de Brito Magalhães CL, et al. Diet supplementation with beta-carotene improves the serum lipid profile in rats fed a cholesterol-enriched diet. J Physiol Biochem. 2013 Dec;69(4):811-20. PMID: 23645541.

Di Tomo P, Canali R, Ciavardelli D, et al. β-Carotene and lycopene affect endothelial response to TNF-α reducing nitro-oxidative stress and interaction with monocytes. Mol Nutr Food Res. 2012 Feb;56(2):217-27. PMID: 22162208.

Amengual J, Gouranton E, van Helden YG, et al. Beta-carotene reduces body adiposity of mice via BCMO1. PLoS One. 2011;6(6):e20644. PMID: 21673813.

Custom Order

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