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(−)-Epinephrine

(−)-Epinephrine

Product ID E6432
Cas No. 51-43-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $41.00 In stock
5 g $132.60 In stock
10 g $234.70 In stock
100 g $1,021.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

(-)-Epinephrine is the active isomer of epinephrine, an endogenous hormone neurotransmitter. Epinephrine exhibits bronchodilatory, vasoconstrictive and cardiostimulantory/positive inotropic activities. Epinephrine acts as a non-selective agonist at both α- and β-adrenergic receptors, activating the sympathetic nervous system. Epinephrine is clinically used to treat cardiac arrest and anaphylaxis, as it increases cardiac output and peripheral resistance and decreases edema by suppressing leakage from constricted vessels. This compound also inhibits insulin secretion, increases glucagon and adrenocorticotropic hormone (ACTH) secretion, and induces glycogenolysis, glycolysis, and lipolysis to increase energy production.

Product Info

Cas No.

51-43-4

Purity

≥98%

Formula

C9H13NO3

Formula Wt.

183.20

IUPAC Name

4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol

Synonym

Bronkaid Mist, Eppy, Glauposine, Simplene, Suprarenaline

Melting Point

211-212°C

Solubility

Slightly soluble in water and alcohol. Soluble in aqueous solutions of mineral acids, NaOH, and KOH. Insoluble in ether, chloroform or acetone.

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

E6432 MSDS PDF

Info Sheet

E6432 Info Sheet PDF

References

Seravalle G, Dimitriadis K, Dell'Oro R, et al. How to assess sympathetic nervous system activity in clinical practice. Curr Clin Pharmacol. 2013 Aug;8(3):182-8. PMID: 23173963.

Busse PJ, Buckland MS. Non-histaminergic angioedema: focus on bradykinin-mediated angioedema. Clin Exp Allergy. 2013 Apr;43(4):385-94. PMID: 23517034.

Warren JB, Pixley FJ, Dollery CT. Importance of beta 2-adrenoceptor stimulation in the suppression of intradermal antigen challenge by adrenaline. Br J Clin Pharmacol. 1989 Feb;27(2):173-7. PMID: 2565729.

Warren J. The adrenal medulla and the airway. Br J Dis Chest. 1986 Jan;80(1):1-6. PMID: 3004549.

Berecek KH, Brody MJ. Evidence for a neurotransmitter role for epinephrine derived from the adrenal medulla. Am J Physiol. 1982 Apr;242(4):H593-601. PMID: 6278965

Custom Order

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