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5-Fluorocytosine

5-Fluorocytosine

Product ID F4581
Cas No. 2022-85-7
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $52.50 In stock
1 g $78.80 In stock
5 g $157.50 In stock
10 g $288.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

5-Fluorocytosine, or Flucytosine, is a synthetic fluorinated pyrimidine analog that is used as an antifungal agent. In the presence of the enzyme cytosine deaminase it is converted to 5-fluorouracil, an antimetabolite that is an inhibitor of thymidylate synthase.

Product Info

Cas No.

2022-85-7

Purity

≥98%

Formula

C4H4FN3O

Formula Wt.

129.09

Chemical Name

6-amino-5-fluoro-2(1H)-pyrimidinone

IUPAC Name

4-Amino-5-fluoro-2(1H)-pyrimidinone

Synonym

Flucytosine, Ancobon, Ancotil, 5-FC, NSC 103805, Ro 2-9915

Solubility

Soluble in water (1.5 g/100 mL or 0.089 M).

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

F4581 MSDS PDF

Info Sheet

F4581 Info Sheet PDF

References

Huang TT, Parab S, Burnett R, et al. Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model. Hum Gene Ther. 2015 Feb; 26(2):82-93. PMID: 25419577.

Davoudi N, Khamesipour A, Mahboudi F, McMaster WR. A dual drug sensitive L. major induces protection without lesion in C57BL/6 mice. PLoS Negl Trop Dis. 2014 May 29; 8(5):e2785. PMID: 24873970.

O’Connor L, Livermore J, Sharp AD, et al. Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients. J Infect Dis. 2013 Jul 15; 208(2):351-361. PMID: 23599314.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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