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5-Fluorouracil

5-Fluorouracil

Product ID F4480
Cas No. 51-21-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $43.90 In stock
5 g $114.20 In stock
25 g $360.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

5-Fluorouracil (5-FU) is an antimetabolite pyrimidine analog that exhibits anticancer chemotherapeutic activity; it inhibits thymidylate synthase, preventing thymidine synthesis. 5-FU is clinically used to treat various cancers and is often co-administered with other chemotherapeutics to decrease its peripheral cytotoxicity.

Product Info

Cas No.

51-21-8

Purity

≥98%

Formula

C4H3FN2O2

Formula Wt.

130.08

Chemical Name

5-Fluoro-2,4(1H,3H)-pyrimidinedione

IUPAC Name

5-fluoro-1H-pyrimidine-2,4-dione

Synonym

Fluorouracil, 5-FU, 2,4-dioxo-5-fluoropyrimidine

Melting Point

282-283°C(dec.)

Solubility

Slightly soluble in water (12 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F4480 MSDS PDF

Info Sheet

F4480 Info Sheet PDF

References

Papanastasopoulos P, Stebbing J. Molecular basis of 5-fluorouracil-related toxicity: lessons from clinical practice. Anticancer Res. 2014 Apr;34(4):1531-5. PMID: 24692679.

Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003 May;3(5):330-8. PMID: 12724731.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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