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5,6-Dehydrokawain

5,6-Dehydrokawain

Product ID D1628
Cas No. 1952-41-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $147.20 In stock
5 mg $280.40 In stock
10 mg $433.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

5,6-Dehydrokawain is a kavalactone originally found in Piper methysticum (kava plant) and Alpinia that exhibits neuroprotective and antithrombotic activities. 5,6-Dehydrokawain inhibits aggregation and ATP release of platelets as well as formation of thromboxane B2 (TxB2). Additionally, this compound prevents H2O2-induced toxicity, decreasing release of lactate dehydrogenase, activation of caspase 3, and oxidative stress in neurons.

Product Info

Cas No.

1952-41-6

Purity

≥98%

Formula

C14H12O3

Formula Wt.

228.25

IUPAC Name

4-methoxy-6-[(E)-2-phenylethenyl]pyran-2-one

Melting Point

138-140°C

Appearance

White/ Off White Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D1628 MSDS PDF

Info Sheet

D1628 Info Sheet PDF

References

Rao YK, Shih HN, Lee YC, et al. Purification of kavalactones from Alpinia zerumbet and their protective actions against hydrogen peroxide-induced cytotoxicity in PC12 cells. J Biosci Bioeng. 2014 Jun 11. [Epub ahead of print]. PMID: 24929995.

Teng CM, Hsu SY, Lin CH, et al. Antiplatelet action of dehydrokawain derivatives isolated from Alpinia speciosa rhizoma. Chin J Physiol. 1990;33(1):41-8. PMID: 2376215.

Custom Order

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