Description
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
| Cas No. | 59277-89-3 |
|---|---|
| Purity | ≥98% |
| Formula | C8H11N5O3 |
| Formula Wt. | 225.20 |
| Chemical Name | Acycloguanosine; Vipral; Zovirax |
| IUPAC Name | 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one |
| Melting Point | 256.5-257°C |
| Solubility | Slightly soluble in water (0.7 mg/mL). Soluble in 1 M HCl (50 mg/mL), DMSO (7 mg/mL). |
| Appearance | White Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.
Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.
Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.
Peptide hormone, neurotensin analog found in am...
Semi-synthetic derivative of chlorophyll; food ...
AMPA positive allosteric modulator, D2, 5-HT2A,...
c-MET and Ron inhibitor.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Polyvinyl pyrrolidone polymer, disinfectant.
Vitamin A derivative, palmitic acid ester of re...
Flavanone found in species of Citrus. Naringen...
PORCN inhibitor.
Neuroactive mycotoxin produced by Penicillum an...
Xanthine derivative; adenosine antagonist, PDE ...
Amino acid precursor of dopamine.
Coumarin lactone found in chicory and other pla...
Phenylpropanoid found in Castilleja, Verbena, V...
Synthesis impurity
Thalidomide derivative; cereblon and TNF-α inh...
Benzothiazepine; L-type Ca2+ channel blocker, p...
Statin; HMG-CoA reductase inhibitor.
TLR4 inhibitor.
STING inhibitor