Description
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
| Cas No. | 59277-89-3 |
|---|---|
| Purity | ≥98% |
| Formula | C8H11N5O3 |
| Formula Wt. | 225.20 |
| Chemical Name | Acycloguanosine; Vipral; Zovirax |
| IUPAC Name | 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one |
| Melting Point | 256.5-257°C |
| Solubility | Slightly soluble in water (0.7 mg/mL). Soluble in 1 M HCl (50 mg/mL), DMSO (7 mg/mL). |
| Appearance | White Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.
Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.
Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.
Synthetic steroid hormone used in HRT; SERM, PR...
Read-through agent and nonsense mutation target...
Isoquinoline alkaloid found in Corydalis, Phell...
Snake venom found in Bothrops alternatus urutu....
Histamine H2 inverse agonist.
HDAC inhibitor, RNA splicing modulator.
Nitrogen mustard, DNA alkylator.
Jumonji histone demethylase inhibitor.
Ca2+ sensitizer; ATP-sensitive K+ channel activ...
Sulfonylurea; SUR1 antagonist.
Nucleoside (thymidine) analog.
Antimicrobial peptide found in Hyalophora cecro...
Phenol found in Psoralea coryfolia.
Methimazole prodrug; thyroid peroxidase inhibit...
Immunostimulator, adjuvant.
5-HT7 and D2/3 antagonist.
Nitrogen mustard, DNA alkylator.
Xanthine derivative; PDE inhibitor.
H+/K+ ATPase inhibitor.
Microtubule depolymerization inhibitor.