Description
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
| Cas No. | 59277-89-3 |
|---|---|
| Purity | ≥98% |
| Formula | C8H11N5O3 |
| Formula Wt. | 225.20 |
| Chemical Name | Acycloguanosine; Vipral; Zovirax |
| IUPAC Name | 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one |
| Melting Point | 256.5-257°C |
| Solubility | Slightly soluble in water (0.7 mg/mL). Soluble in 1 M HCl (50 mg/mL), DMSO (7 mg/mL). |
| Appearance | White Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.
Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.
Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.
Imidazoline and α2-adrenergic agonist, Nav1.7 ...
Peptide, fibrinogen E analog found in Amaranthu...
Tropane alkaloid found in Solanaceae plants; M1...
ROCK1/2 inhibitor.
Endogenous peptide hormone, involved in secreti...
Quaternary base alkaloid found in Phellodendron...
Cysteine-ITC conjugate, antioxidant.
Polyphenolic compound present in black tea.
HIV protease inhibitor.
Sesquiterpene found in Curcuma.
Broad-spectrum antiviral activity against SARS-...
Aminoquinoline, binds heme, causes cell lysis.<...
PP2A activator, Sphk1 and PKC inhibitor.
Cytarabine derivative, nucleoside (cytosine) an...
Alpha blocker and vasoactive agent.
Atypical amino acid found in Isaria sinclairi, ...
Fungal pigment found in red yeast rice
TRPC5, NS4B, histamine H1 inhibitor.
Found in Paeonia; L-type Ca2+ channel blocker.<...
Derivative of aristolochic acid found in Asarum...