• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Adapalene

Adapalene

Product ID A1202
Cas No. 106685-40-9
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $214.00 In stock
250 mg $377.70 In stock
1 g $956.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Adapalene is a derivative of tretinoin that is clinically used to treat acne and pityriasis versicolor. This synthetic retinoid exhibits anti-inflammatory activity, decreasing expression of Ki67, α2-integrin, α6-integrin, toll-like receptor 2 (TLR2), IL-8, and β-defensin in ex vivo models. Like other retinoids, adapalene also activates retinoic acid receptors RARα/β/γ across several models.

Product Info

Cas No.

106685-40-9

Purity

≥98%

Formula

C28H28O3

Formula Wt.

412.52

IUPAC Name

6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid

Melting Point

319-322C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A1202 MSDS PDF

Info Sheet

A1202 Info Sheet PDF

References

Tirado-Sánchez A, Espíndola YS, Ponce-Olivera RM, et al. Efficacy and safety of adapalene gel 0.1% and 0.3% and tretinoin gel 0.05% for acne vulgaris: results of a single-center, randomized, double-blinded, placebo-controlled clinical trial on Mexican patients (skin type III-IV). J Cosmet Dermatol. 2013 Jun;12(2):103-7. PMID: 23725303.

Shi TW, Ren XK, Yu HX, et al. Roles of adapalene in the treatment of pityriasis versicolor. Dermatology. 2012;224(2):184-8. PMID: 22572567.

Zuliani T, Khammari A, Chaussy H, et al. Ex vivo demonstration of a synergistic effect of Adapalene and benzoyl peroxide on inflammatory acne lesions. Exp Dermatol. 2011 Oct;20(10):850-3. PMID: 21793939.

Michel S, Jomard A, Démarchez M. Pharmacology of adapalene. Br J Dermatol. 1998 Oct;139 Suppl 52:3-7. PMID: 9990413.

Bernard BA. Adapalene, a new chemical entity with retinoid activity. Skin Pharmacol. 1993;6 Suppl 1:61-9. PMID: 8142113.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A6922

    Arformoterol Tartrate

    R,R enantiomer of formoterol; β2-adrenergic an...

    ≥98%
  • C9708

    CYC-116

    AurKB/C inhibitor.

    ≥98%
  • R5974

    Rosuvastatin Calcium

    Statin; HMG-CoA reductase inhibitor, potential ...

    ≥98%
  • S8045

    S-Sulforaphane

    Synthetic antioxidant that induces phase II enz...

    ≥96%
  • S8248

    Sulfamethoxazole

    Sulfonamide; PABA inhibitor.

    ≥98%
  • R176485

    Remdesivir

    SARS-CoV-2 inhibitor

    ≥99%
  • O9334

    Oxibendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • G5752

    Gonadorelin Acetate

    Synthetic peptide, GnRH derivative; GnRH agonist.
    ≥95%
  • A4803

    Amantadine Sulfate

    Viral M2 proton channel blocker, MAO-A, NET, NM...

    ≥98%
  • R5773

    Rosiglitazone

    Thiazolidinedione; PPARγ agonist.

    ≥99%
  • A5228

    Angiogenin

    Small protein, cleaves RNA.

    ≥98%
  • C0021

    Cafestol Acetate

    Diterpene found in brewed, unfiltered coffee; F...

    ≥98%
  • S0132

    Saikosaponin A

    Triterpene saponin found in Bupleurum.

    ≥98%
  • B1746

    Belinostat

    HDAC inhibitor.

    ≥98%
  • S8345

    S-(−)-Sulpiride

    GHB agonist, D2/3 antagonist.

    ≥99%
  • S5869

    Sorafenib Tosylate

    c-Raf, RET, VEGFR1 inhibitor, potential HMT inh...

    ≥99%
  • E537331

    Enniatin Complex

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • T0092

    1-Hydroxybaccatin I

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • S7600

    Staurosporine

    Alkaloid produced by Streptomyces, precursor in...

    ≥98%
  • G6368

    GPR

    Peptide, fibrinogen E analog found in Amaranthu...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only