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AK-7

AK-7

Product ID A4002
Cas No. 420831-40-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $99.80 In stock
25 mg $315.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AK-7 is an inhibitor of sirtuin 2 (SIRT2); sirtuins are considered class III histone deacetylases (HDACs). AK-7 exhibits neuroprotective activity, decreasing brain atrophy and improving motor function and survival in animal models of Huntington’s disease.

Product Info

Cas No.

420831-40-9

Purity

≥98%

Formula

C19H21BrN2O3S

Formula Wt.

437.35

IUPAC Name

3-(azepan-1-ylsulfonyl)-N-(3-bromophenyl)benzamide

Synonym

AK7

Solubility

100mM in DMSO

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A4002 MSDS PDF

Info Sheet

A4002 Info Sheet PDF

References

Chopra V, Quinti L, Kim J, et al. The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models. Cell Rep. 2012 Dec 27;2(6):1492-7. PMID: 23200855.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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