Description
Alytesin is an antimicrobial peptide (AMP) originally found in the skin of amphibians. Alytesin decreases gastric acid secretion, decreasing food intake in vivo and exhibiting anorexigenic activity.
Alytesin
Product ID A4498
Cas No. 31078-12-3
Purity ≥95%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 31078-12-3 |
|---|---|
| Purity | ≥95% |
| Formula | C68H106N22O17S |
| Formula Wt. | 1535.8 |
| IUPAC Name | (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4- methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]- 3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl- 1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1- oxopropan-2-yl]-2-[[(2S, 3R)-2-[[2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[[(2S)-5- oxopyrrolidine-2-carbonyl]amino]acetyl]amino]pentanoyl]amino]-4- methylpentanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino] pentanediamide |
| Solubility | Soluble in water (1 mg/mL). |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
König E, Zhou M, Wang L, et al. Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): implications for the evolution of frog skin defensive secretions. Toxicon. 2012 Nov;60(6):967-81. PMID: 22800568
Cline MA, Fouse DN, Prall BC. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. PMID: 18384875.
Guglietta A, Strunk CL, Irons BJ, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. Erratum in: Peptides 1987 May-Jun;8(3):579. PMID: 3841693.