Description
Alytesin is an antimicrobial peptide (AMP) originally found in the skin of amphibians. Alytesin decreases gastric acid secretion, decreasing food intake in vivo and exhibiting anorexigenic activity.
| Product Unit Size | Cost | Quantity | Stock |
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Alytesin is an antimicrobial peptide (AMP) originally found in the skin of amphibians. Alytesin decreases gastric acid secretion, decreasing food intake in vivo and exhibiting anorexigenic activity.
| Cas No. | 31078-12-3 |
|---|---|
| Purity | ≥95% |
| Formula | C68H106N22O17S |
| Formula Wt. | 1535.8 |
| IUPAC Name | (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4- methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]- 3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl- 1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1- oxopropan-2-yl]-2-[[(2S, 3R)-2-[[2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[[(2S)-5- oxopyrrolidine-2-carbonyl]amino]acetyl]amino]pentanoyl]amino]-4- methylpentanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino] pentanediamide |
| Solubility | Soluble in water (1 mg/mL). |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
König E, Zhou M, Wang L, et al. Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): implications for the evolution of frog skin defensive secretions. Toxicon. 2012 Nov;60(6):967-81. PMID: 22800568
Cline MA, Fouse DN, Prall BC. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. PMID: 18384875.
Guglietta A, Strunk CL, Irons BJ, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. Erratum in: Peptides 1987 May-Jun;8(3):579. PMID: 3841693.
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