Description
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
| Product Unit Size | Cost | Quantity | Stock |
|---|
CVT-313 is a potent and selective inhibitor of cyclin-dependent kinase 2 (CDK2).
| Cas No. | 199986-75-9 |
|---|---|
| Purity | ≥98% |
| Formula | C22H28N6O3 |
| Formula Wt. | 400.48 |
| IUPAC Name | 2,2'-({9-Isopropyl-6-[(4-methoxybenzyl)amino]-9H-purin-2-yl}imino)diethanol |
| Synonym | CVT313; Cdk2 Inhibitor III; Cyclin-dependent kinase 2 Inhibitor III |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Brooks E., Gray N., et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J Biol Chem. 272(46):29207-11 (1997). PMID: 9360999.
Faber A., Chiles T. Inhibition of cyclin-dependent kinase-2 induces apoptosis in human diffuse large B-cell lymphomas. Cell Cycle. 6(23):2982-9 (2007). PMID: 18156799.
Isothiocyanate found in cruciferous vegetables,...
Recombinant HIV core protein antigen fragment.<...
Imidazole; 14-α demethylase inhibitor.
Cysteine-ITC conjugate, antioxidant.
Endogenous peptide hormone fragment, involved i...
BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.
Nitrosourea, DNA cross-linker.
Amino amide; voltage-gated Na+, BK/SK, Kv1, Kv3...
H1 histamine and LT antagonist, PDE inhibitor.<...
NMDA potentiator, GABA-A antagonist.
Diclofenac analog, NSAID; COX-2 inhibitor.
β2-adrenergic agonist.
FIASMA, SERT and DAT inhibitor, α1-adrenergic ...
Heterocyclic light-emitting compound, natural l...
FIASMA, L-type Ca2+ channel blocker, D2 antagon...
Fluoroquinolone; bacterial DNA gyrase inhibitor...
p110δ PI3K inhibitor.
Cyclic sesquiterpene found in ginger root; pote...
Nucleoside (thymidine) analog; RT inhibitor.
Synthetic steroid hormone, contraceptive; PR ag...