Description
Amitraz is an agonist at α-adrenergic receptors that displays insecticide activity. Amitraz also inhibits monoamine oxidase (MAO) and synthesis of prostaglandins. Additionally, amitraz may act on octopamine receptors. Amitraz acts as an acaricide and is commonly used in veterinary prophylaxis against flea and tick infections. Amitraz may inhibit β-cell insulin release in mammals.