• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Amyloid-β (1-40)

Amyloid-β (1-40)

Product ID A4848
Cas No. 131438-79-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $824.50 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Amyloid-β (Aβ) is a peptide cleavage product of amyloid precursor protein (APP) that is often used as a biomarker in Alzheimer’s disease. Misfolded Aβ oligomers instigate conformation changes in other, normally folded Aβ oligomers, increasing the number of misfolded proteins and eventually forming neurotoxic plaques. These plaques impair cognitive performance in vivo. Aβ (1-42) is more fibrillogenic and more highly associated with Alzheimer’s disease than Aβ (1-40), although the shorter form is more common.

Product Info

Cas No.

131438-79-4

Purity

≥98%

Formula

C194H295N53O58S

Formula Wt.

4329.8

Synonym

Amyloid-beta protein fragment (1-40)

Solubility

Soluble in water (~6mg/mL). Not directly soluble in buffer or saline.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A4848 MSDS PDF

Info Sheet

A4848 Info Sheet PDF

References

Hu J, el-Fakahany EE. Neuroreport. 4(6):760-762 (1993).Jia J, Kang L, Li S, et al. Amelioratory effects of testosterone treatment on cognitive performance deficits induced by soluble Aβ1-42 oligomers injected into the hippocampus. Horm Behav. 2013 Aug;64(3):477-86. PMID: 23954394.

Yin YI, Bassit B, Zhu L, et al. gamma-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: Implications for Alzheimer Disease. J Biol Chem. 2007 Aug 10;282(32):23639-44. PMID: 17556361.

Hartmann T, Bieger SC, Brühl B, et al. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med. 1997 Sep;3(9):1016-20. PMID: 9288729.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • V024761

    Vatalanib

    Inhibitor of VEGFR1/2/3.

    ≥98%
  • S4932

    SMI-4a

    Thiazolidine; Pim kinase inhibitor.

    ≥99%
  • A7200

    AS-252424

    p110γ PI3K inhibitor, potential TRPC1/5/6 nega...

    ≥98%
  • A724092

    Asciminib Hydrochloride

    Allosteric inhibitor

    ≥98%
  • G4782

    Glucoraphenin Potassium

    Glucosinolate found in cruciferous vegetables.<...

    ≥98%
  • H1658

    Heparin Sodium

    Endogenous glycosaminoglycan that is produced b...

    Bioassay ≥140 U/mg
  • C002041

    Cabazitaxel

    Taxoid that disrupts the microtubular network i...

    ≥98%
  • V3326

    Virginiamycin S1

    Macrolide antibiotic; peptidyl transferase inhi...

    ≥99%
  • I5414

    Indapamide

    Thiazide-like diuretic; Kv7.1 and minK K+ chann...

    ≥98%
  • A5278

    Angiotensin III, human

    Endogenous peptide, cleavage product of AT II; ...

    ≥95%
  • S8013

    [Tyr8]-Substance P

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • M0278

    Matrine

    Alkaloid found in Sophora.

    ≥98%
  • O1200

    Odanacatib

    Cathepsin K inhibitor.

    ≥99%
  • S3345

    Silymarin

    Flavonolignan mixture found in Silybum (milk th...

    ≥50% sylibin
  • B6807

    [Des-Arg9]-Bradykinin

    Natriuretic, vasodilatory peptide, bradykinin a...

    ≥95%
  • C000078

    C-178

    STING inhibitor

    ≥99%
  • C9711

    Cyclovirobuxine D

    Found in Buxus; hERG K+ channel inhibitor.

    ≥97%
  • O6932

    Oridonin

    Diterpenoid found in Rabdosia rubescens; potent...

    ≥98%
  • P0010

    Pituitary Adenylate Cyclase-activating Polypeptide-related Peptide, human

    Peptide, involved in paracrine and autocrine ce...

    ≥95%
  • V014457

    Valnemulin Hydrochloride

    Pleuromutilin

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only