• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Anastrozole

Anastrozole

Product ID A5302
Cas No. 120511-73-1
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $90.80 In stock
100 mg $191.50 In stock
250 mg $352.30 In stock
1 g $1,070.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Anastrozole is a third generation aromatase inhibitor that suppresses synthesis of estrogen. Anastrozole exhibits anticancer chemotherapeutic activity and is clinically used to treat ER-positive breast cancer. In vitro, anastrozole inhibits proliferation of cancer cells by disrupting the mitochondrial membrane potential and inducing apoptosis. Because of its anti-estrogen properties, anastrozole may decrease bone mineral density and increase fracture risk.

Product Info

Cas No.

120511-73-1

Purity

≥99%

Formula

C17H19N5

Formula Wt.

293.37

Chemical Name

2,2'-(5-(IH-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropiononitrile)

IUPAC Name

2-[3-(2-cyanopropan-2-yl)-5-(1,2, 4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile

Synonym

ZD1033 Pure, Zeneca ZD1033

Melting Point

81-84°C

Solubility

soluble in methanol, acetone, ethanol (59 mg/mL), THF, ethyl acetate, chloroform, DMSO (40 mg/mL). Slightly soluble in water.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A5302 MSDS PDF

Info Sheet

A5302 Info Sheet PDF

References

Kelly CM, Buzdar AU. Anastrozole. Expert Opin Drug Saf. 2010 Nov;9(6):995-1003. PMID: 20923259.

Hong Y, Chen S. Aromatase inhibitors: structural features and biochemical characterization. Ann N Y Acad Sci. 2006 Nov;1089:237-51. PMID: 17261771.

McCloskey E. Effects of third-generation aromatase inhibitors on bone. Eur J Cancer. 2006 May;42(8):1044-51. PMID: 16554149.

Xanthopoulos JM, Romano AE, Majumdar SK. Response of Mouse Breast Cancer Cells to Anastrozole, Tamoxifen, and the Combination. J Biomed Biotechnol. 2005;2005(1):10-19. PMID: 15689634.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C2945

    Chlorophyllin Sodium-Copper Salt

    Semi-synthetic derivative of chlorophyll; food ...

    USP 28
  • M721002

    MSA-2

    STING agonist

    ≥98%
  • R3347

    Riluzole

    Benzothiazole; TRPC5 agonist, PTR1 inhibitor, v...

    ≥98%
  • G0248

    (-)-Gambogic Acid

    Xanthone found in Garcinia hanburyi.

    ≥99%
  • P6002

    PP-121

    p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR...

    ≥98%
  • A5033

    4-Aminosalicylic Acid

    Dihydrofolate reductase inhibitor.

    ≥98%
  • D0244

    Dalcetrapib

    Cholesterol ester transfer protein inhibitor.

    ≥98%
  • O9234

    Oxiconazole Nitrate

    Imidazole; 14-α demethylase inhibitor.

    ≥98%
  • T503720

    TMS

    Selective inhibitor of cytochrome P450 1B1 (CYP...

    ≥99%
  • C0278

    (+)-Catechin

    Flavanol originally found in Camilla (green tea...

    ≥99%
  • T7135

    Triticonazole

    Triazole; 14-α demethylase inhibitor, potentia...

    ≥95%
  • F8149

    Fumonisin B1

    Mycotoxin produced by Fusarium; sphingosine acy...

    ≥98%
  • K5604

    Kobe 0065

    Ras inhibitor.

    ≥99%
  • G7440

    GSK-1120212

    MEK1/2 inhibitor.

    ≥98%
  • B1879

    Betamethasone Valerate

    Synthetic steroid hormone; glucocorticoid agoni...

    ≥98%
  • G4596

    Glycidamide

    Epoxide metabolite of acrylamide, induces DNA a...

    ≥98%
  • H0001

    H7

    PKC and PKG inhibitor.

    ≥98%
  • D6957

    Droloxifene

    Triphenylthylene, tamoxifen analog; SERM.

    ≥98%
  • B6807

    [Des-Arg9]-Bradykinin

    Natriuretic, vasodilatory peptide, bradykinin a...

    ≥95%
  • A4940

    6-Aminonicotinamide

    G6PDH inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only