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Ascorbyl palmitate is a fat-soluble vitamin C derivative that is commercially used as a vitamin C supplement and antioxidative food additive; it is also used in research models to aid in drug delivery or tissue targeting. Ascorbyl palmitate is the ester of ascorbic acid and palmitic acid. In porcine skin, this compound decreases free radical formation.
| Cas No. | 137-66-6 |
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| Purity | ≥95% |
| Formula | C22H38O7 |
| Formula Wt. | 414.53 |
| Chemical Name | L-Ascorbic acid, 6-palmitate |
| IUPAC Name | [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] hexadecanoate |
| Synonym | Ascorbic acid palmitate, Ascorbic palmitate, Quicifal, Ondascora, Vitamin C palmitate, 6-Palmitoylascorbic acid |
| Melting Point | 107-117°C |
| Solubility | Insoluble in water. Soluble in ethanol (8 mg/mL). |
| Appearance | White to off-white powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
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| Info Sheet |
Zariwala MG, Farnaud S, Merchant Z, et al. Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: preparation, characterisation and in vitro evaluation. Colloids Surf B Biointerfaces. 2014 Mar 1;115:86-92. PMID: 24333557.
Let MB, Jacobsen C, Meyer AS. Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently. J Agric Food Chem. 2007 Mar 21;55(6):2369-75. PMID: 17319681.
Llabot JM, Palma SD, Manzo RH, et al. Design of novel antifungal mucoadhesive films. Part II. Formulation and in vitro biopharmaceutical evaluation. Int J Pharm. 2007 May 24;336(2):263-8. PMID: 17223291.
Jurkovic P, Sentjurc M, Gasperlin M, et al. Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions. Eur J Pharm Biopharm. 2003 Jul;56(1):59-66. PMID: 12837482.