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Atomoxetine Hydrochloride

Atomoxetine Hydrochloride

Product ID A7656
Cas No. 82248-59-7
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $127.90 In stock
25 mg $239.60 In stock
100 mg $788.90 In stock
250 mg $1,408.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Atomoxetine hydrochloride, also known as tomoxetine hydrochloride, is a commonly prescribed treatment for a variety of ADHD subtypes. This compound also displays minor antidepressant activity, but is not active enough of its own to warrant prescription use as a treatment for depression. Atomoxetine hydrochloride inhibits norepinephrine transporters (NET), increasing norepinephrine and dopamine levels, and inhibits serotonin transporters (SERT) and N-methyl D-aspartate (NMDA) receptors to a lesser degree. Perhaps due to its modulation of neurotransmitters, atomoxetine is also currently being studied as a potential relapse prevention therapy in recently abstinent substance abuse subjects.

Product Info

Cas No.

82248-59-7

Purity

≥99%

Formula

C17H21NO • HCl

Formula Wt.

291.82

IUPAC Name

(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;hydrochloride

Synonym

Strattera, tomoxetine, attentin

Melting Point

163-168°C

Solubility

Soluble in water (27.8mg/mL). DMSO 58 mg/mL. Ethanol 37 mg/mL. Chloroform, methanol.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A7656 MSDS PDF

Info Sheet

A7656 Info Sheet PDF

References

Isaksson J, Hogmark A, Nilsson KW, et al. Effects of stimulants and atomoxetine on cortisol levels in children with ADHD. Psychiatry Res. 2013 Jul 11. pii: S0165-1781 PMID: 23850434.

Ercan ES, Akyol Ardic U, Kabukcu Basay B, et al. Atomoxetine response in the inattentive and combined subtypes of attention deficit hyperactivity disorder: a retrospective chart review. Atten Defic Hyperact Disord. 2013 Jun 5. [Epub ahead of print]. PMID: 23737214.

Silverstone PH, Dadashova R. Atomoxetine treatment for nicotine withdrawal: a pilot double-blind, placebo-controlled, fixed-dose study in adult smokers. Ann Gen Psychiatry. 2012 Mar 9;11(1):6. PMID: 22405499.

Economidou D, Dalley JW, Everitt BJ. Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking. Biol Psychiatry. 2011 Feb 1;69(3):266-74. PMID: 21109233.

Ludolph AG, Udvardi PT, Schaz U, et al. Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations. Br J Pharmacol. 2010 May;160(2):283-91. PMID: 20423340.

Custom Order

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