Description
Atracurium is a reversible inhibitor of acetylcholine receptors (AChRs) that acts as a non-depolarizing neuromuscular junction blocker (NMJ); it causes muscular paralysis and is clinically used as an anesthetic.
Atracurium Besylate
Product ID A7668
Cas No. 64228-81-5
Purity ≥95%
| Product Unit Size | Cost | Quantity | Stock |
|---|
Product Info
| Cas No. | 64228-81-5 |
|---|---|
| Purity | ≥95% |
| Formula | C53H72N2O12 • (C6H5O3S)2 |
| Formula Wt. | 1243.49 |
| Chemical Name | 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-yl]propanoyl- oxy]pentyl-3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7- dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2- yl]propanoate |
| IUPAC Name | benzenesulfonate;5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6, 7-dimethoxy-2-methyl-3, 4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3, 4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate |
| Synonym | BW-33A, Tracrium |
| Melting Point | 185-194°C |
| Solubility | Soluble in water (27 mg/mL). Soluble in DMSO (>100 mg/mL). |
| Appearance | White/yellow crystalline powder |
Shipping and Storage
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Shashank D, Singh NR, Singh LK. Effects of pretreatment with different neuromuscular blocking agents on facilitation of intubation with rocuronium: A prospective randomized comparative study. Indian J Anaesth. 2014 May;58(3):303-8. PMID: 25024474.
Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.
Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.