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AZ-5104

AZ-5104

Product ID A980005
Cas No. 1421373-98-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $89.00 In stock
25 mg $252.00 In stock
100 mg $538.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AZ-5104 is an active metabolite of AZD-9291 (osimertinib), an inhibitor of EGFR. It has shown efficacy in models of non-small cell lung cancer.

Product Info

Cas No.

1421373-98-9

Purity

≥98%

Formula

C27H31N7O2

Formula Wt.

485.59

IUPAC Name

N-(2-{[2-(Dimethylamino)ethyl](methyl)amino}-5-{[4-(1H-indol-3-yl)-2-pyrimidinyl]amino}-4-methoxyphenyl)acrylamide

Synonym

AZ-5104, AZ 5104, AZ5104

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A980005 MSDS PDF

Info Sheet

A980005 Info Sheet PDF

References

Yates J. Ashton S., et al. Irreversible Inhibition of EGFR: Modeling the Combined Pharmacokinetic-Pharmacodynamic Relationship of Osimertinib and Its Active Metabolite AZ5104. Mol Cancer Ther. 15(10):2378-87 (2016). PMID: 27439477.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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