Description
Bambuterol is a long-acting β2-adrenergic agonist and inhibitor of butylcholinesterase (BChE). Bambuterol is a prodrug of terbutaline and exhibits bronchodilatory and anti-asthma activities.
Bambuterol Hydrochloride
Product ID B0150
Cas No. 81732-46-9
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 81732-46-9 |
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| Purity | ≥98% |
| Formula | C18H29N3O5 • HCl |
| Formula Wt. | 403.91 |
| Chemical Name | Dimethylcarbamic acid 5-[2-[(1,1-dimethylethyl)- amino]-1-hydroxyethyl]-1,3-phenylene ester hydrochloride |
| IUPAC Name | [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate;hydrochloride |
| Synonym | KWD-2183, Bambec |
| Melting Point | 222-224°C |
| Solubility | Soluble in water (33mg/mL). |
| Appearance | White or Almost White Crystalline Powder |
Shipping and Storage
| Store Temp | 4°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Wu J, Tan Z, Pistolozzi M, et al. Rivastigmine-bambuterol hybrids as selective butyrylcholinesterase inhibitors. Molecules. 2023 Dec 22;29(1):72. PMID: 38202655.
Mohr F, Zimmermann M, Klein J. Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BuChE inhibition. Neuropharmacology. 2013 Apr;67:37-45. PMID: 23147415.
Bosak A, Gazić I, Vinković V, et al. Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers. Chem Biol Interact. 2008 Sep 25;175(1-3):192-5. PMID: 18582854.
Waldeck B. Beta-adrenoceptor agonists and asthma--100 years of development. Eur J Pharmacol. 2002 Jun 7;445(1-2):1-12. PMID: 12065188.