Description
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
Product Unit Size | Cost | Quantity | Stock |
---|
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
Cas No. | 1375469-38-7 |
---|---|
Purity | ≥98% |
Formula | C25H30N6O5 |
Formula Wt. | 494.55 |
IUPAC Name | N-{8-[(2R)-2-Hydroxy-3-(4-morpholinyl)propoxy]-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-2-methylnicotinamide |
Synonym | BAY 1082439, BAY1082439, BAY10-82439, BAY 10-82439, BAY-10-82439 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Zou Y., Qi Z., et al. Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3Kα/β/δ Inhibitor BAY1082439. Mol Cancer Ther. 17(10):2091-99 (2018). PMID: 30045927.
Diterpene component of vitamin A, differentiati...
Citalopram analog
Thienylbutyl ITC analog.
α1-adrenergic antagonist.
Serum response factor inhibitor and MRTF-A bind...
NSAID; COX-2 inhibitor.
Synthesis impurity
Thienopyridine; P2Y12 antagonist.
Smoothened agonist.
p110α PI3K and mTOR inhibitor.
Lignan found in Magnolia; GABA-A potentiator.
Semi-synthetic taxane.
Monoterpene; nAChR antagonist.
Induces cardiomyogenic effects in pluripotent c...
B-Raf inhibitor.
DNA alkylator.
Broad-spectrum antibiotic
Fumaric acid methyl ester; nAChR agonist, indir...
Lignan found in species of Magnolia; GABA-A pot...
Benzofuroxan derivative; MDMX inhibitor.