Description
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Cas No. | 1375469-38-7 |
|---|---|
| Purity | ≥98% |
| Formula | C25H30N6O5 |
| Formula Wt. | 494.55 |
| IUPAC Name | N-{8-[(2R)-2-Hydroxy-3-(4-morpholinyl)propoxy]-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-2-methylnicotinamide |
| Synonym | BAY 1082439, BAY1082439, BAY10-82439, BAY 10-82439, BAY-10-82439 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zou Y., Qi Z., et al. Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3Kα/β/δ Inhibitor BAY1082439. Mol Cancer Ther. 17(10):2091-99 (2018). PMID: 30045927.
Endogenous peptide hormone, somatostatin analog...
Sesquiterpene lactone found in Artemisia (wormw...
Oxyindole alkaloid found in Uncaria sinensis; h...
AurKB/C inhibitor.
Galactose analog, allolactose mimic, induces ac...
Lincosamide; peptidyl transferase inhibitor, pr...
Mycotoxin produced by species of Aspergillus; D...
Kavalactone originally found in Piper methystic...
Minor kavalactone originally found in Piper met...
Aromatase inhibitor.
Sulfonamide; dihydropteroate synthase inhibitor...
Synthetic ITC, erysolin analog.
mTOR inhibitor.
MAO-A/B inhibitor.
Diterpene found in Taxus.
Potential VEGFR2, Met, RET, Axl, Ron, PDGFR, FG...
Aminoglycoside; protein translation inhibitor.<...
Saponin found in Polygala.
COMT inhibitor.
principal metabolic product of COX-2