Description
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Cas No. | 1375469-38-7 |
|---|---|
| Purity | ≥98% |
| Formula | C25H30N6O5 |
| Formula Wt. | 494.55 |
| IUPAC Name | N-{8-[(2R)-2-Hydroxy-3-(4-morpholinyl)propoxy]-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-2-methylnicotinamide |
| Synonym | BAY 1082439, BAY1082439, BAY10-82439, BAY 10-82439, BAY-10-82439 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zou Y., Qi Z., et al. Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3Kα/β/δ Inhibitor BAY1082439. Mol Cancer Ther. 17(10):2091-99 (2018). PMID: 30045927.
β-lactam cephalosporin; penicillin binding pro...
Steroid produced by Penicillum; PI3K, mTOR, DNA...
Thiazolidine; Pim kinase inhibitor.
Recombinant chimeric protein containing Trepone...
FXR agonist.
Active metabolite of losartan
CCK antagonist.
Phenol found in Zingiber; 5-HT3 antagonist.
STING inhibitor
Small protein, cleaves RNA.
Cap-dependent endonuclease inhibitor
Pyrimidine nucleoside analog; DNA synthesis inh...
Lincosamide; ribosomal translocation and protei...
Organosulfide found in Allium; cholesterol synt...
Microtubule polymerization inhibitor.
Found in Salvia; MAG lipase inhibitor.
Peptide, binds heparin.
Inhibitor of FAK and ALK.
RyR agonist, SIRT, telomerase, P2Y, GPCR inhibi...
Smoothened agonist.