Description
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Cas No. | 1375469-38-7 |
|---|---|
| Purity | ≥98% |
| Formula | C25H30N6O5 |
| Formula Wt. | 494.55 |
| IUPAC Name | N-{8-[(2R)-2-Hydroxy-3-(4-morpholinyl)propoxy]-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-2-methylnicotinamide |
| Synonym | BAY 1082439, BAY1082439, BAY10-82439, BAY 10-82439, BAY-10-82439 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zou Y., Qi Z., et al. Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3Kα/β/δ Inhibitor BAY1082439. Mol Cancer Ther. 17(10):2091-99 (2018). PMID: 30045927.
Aminoglycoside; protein translation inhibitor.<...
L-type Ca2+ channel blocker.
Furanocoumarin found in Psoralea coryfolia, DNA...
Pentacyclic triterpene.
Carcinoembryonic antigen epitope.
Taxane found in Taxus; DNA polymerase inhibitor...
Nitroimidazole, binds DNA; nucleic acid synthes...
Recombinant HIV glycoprotein antigen fragment.<...
Sesquiterpene lactone found in Thapsia, used to...
Phenyl hydrazide; neuronal oxidative stress inh...
Impurity of omeprazole
HIV protease inhibitor.
KRAS inhibitor
Iridoid glycoside found in Gardenia.
BACE1 inhibitor
Focal adhesion kinase (FAK) inhibitor.
Endogenous steroid hormone involved in stress s...
Steroidogenesis inhibitor
Isoflavone, phytoestrogen, found in soy.
Mast cell destabilizer; potential TRP antagonis...