Description
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
| Cas No. | 1375469-38-7 |
|---|---|
| Purity | ≥98% |
| Formula | C25H30N6O5 |
| Formula Wt. | 494.55 |
| IUPAC Name | N-{8-[(2R)-2-Hydroxy-3-(4-morpholinyl)propoxy]-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-2-methylnicotinamide |
| Synonym | BAY 1082439, BAY1082439, BAY10-82439, BAY 10-82439, BAY-10-82439 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zou Y., Qi Z., et al. Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3Kα/β/δ Inhibitor BAY1082439. Mol Cancer Ther. 17(10):2091-99 (2018). PMID: 30045927.
Mycotoxin contaminant found in cereal grains.
DHF reductase inhibitor.
SYK/JAK inhibitor
Fluoroquinolone; bacterial DNA gyrase inhibitor...
β2-adrenergic agonist.
Endogenous hormone and neurotransmitter involve...
Snake venom found in Bothrops neuwiedi diporus;...
Fluoroquinolone; vacuolar H+ ATPase, topoisomer...
Endogenous tachykinin peptide, involved in infl...
Steroid lactone produced by Withania somnifera;...
D2 and 5-HT2A antagonist.
Isoxazole derivative; HSP90 inhibitor.
Triazolopyrazine; c-MET inhibitor.
Nitrogen mustard, DNA alkylator.
Modified nucleotide used for labeling DNA; DNA ...
Organosulfur found in garlic; Kir K+ channel ac...
Diterpene found in Anisomeles.
Microtubule polymerization inhibitor.
Synthetic derivative of selenocyanate.
Polyene, binds ergosterol and induces membrane ...