Description
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Cas No. | 1876467-74-1 |
|---|---|
| Purity | ≥99% |
| Formula | C20H21N7O |
| Formula Wt. | 375.44 |
| IUPAC Name | 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine |
| Synonym | BAY 1895344, BAY1895344 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wengner A., Siemeister G. et al. ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. 77(13 Suppl):Abstract nr 836 (2017).
Ca2+ ionophore.
Polyketide found in Setophoma.
Naturally occurring amino acid found in grains,...
c-Raf inhibitor.
SIRT inhibitor.
Regioisomers
PKA inhibitor.
DAT inhibitor.
Antibacterial (Antimyobacterial) agent.
Actinomycin derivative used to study apoptosis ...
Synthetic prednisolone prodrug; glucocorticoid ...
Endogenous adhesion molecule, binds PKC, calmod...
SIRT1/2 inhibitor, indirect p53 activator.
Diterpene cafestol derivative found in coffee b...
Neurotoxin, mutagen.
Glycoprotein IIb/IIIa inhibitor.
GPR17 agonist, NMDA and fructose 1,6-bisphospha...
Akt inhibitor.
Peptide, used to study cell-surface binding; po...