Description
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Cas No. | 1876467-74-1 |
|---|---|
| Purity | ≥99% |
| Formula | C20H21N7O |
| Formula Wt. | 375.44 |
| IUPAC Name | 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine |
| Synonym | BAY 1895344, BAY1895344 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wengner A., Siemeister G. et al. ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. 77(13 Suppl):Abstract nr 836 (2017).
TRPC5, NS4B, histamine H1 inhibitor.
Impurity of diclofenac
Arp2/3 inhibitor.
Cannabinoid receptor 2 selective agonist.
ACE inhibitor.
Kavalactone originally found in Piper methystic...
Aminocoumarin; bacterial DNA gyrase inhibitor.<...
Cyclic hexapeptide isolated from Phomopsis lept...
Synthesis impurity
Synthetic steroid; glucocorticoid agonist.
AChE inhibitor.
Macrolide antibiotic; peptidyl transferase inhi...
Chk1 inhibitor.
Triterpene saponin found in species of Panax; 2...
Mast cell destabilizer; potential TRP antagonis...
ITC.
Endogenous peptide, involved in vascular contra...
Coenzyme, vitamin found in dairy, meat, eggs, f...
Building block
Heterocyclic light-emitting compound, natural l...