Description
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Cas No. | 1876467-74-1 |
|---|---|
| Purity | ≥99% |
| Formula | C20H21N7O |
| Formula Wt. | 375.44 |
| IUPAC Name | 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine |
| Synonym | BAY 1895344, BAY1895344 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wengner A., Siemeister G. et al. ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. 77(13 Suppl):Abstract nr 836 (2017).
Synthetic type II pyrethroid insecticide; prote...
ITC.
Type A trichothecene mycotoxin produced by Fusa...
Oxidative phosphorylation inhibitor.
Tyrphostin; VEGFR inhibitor.
Flavanol originally found in Camilla (green tea...
PRMT5 inhibitor
Peptidyl transferase inhibitor, protein transla...
Glycoside hydroquinone originally found in Berg...
Immunostimulator, adjuvant.
Polyphenol derivative of caffeic acid found in ...
BHA derivative.
Peptide; peptidoglycan inhibitor.
Triterpene saponin found in species of Panax.
Trichothecene mycotoxin produced by Fusarium.
Bufanolide steroid found in Bufo arenarum;VEGFR...
STING agonist
NSAID; COX-1/2 and PDE inhibitor.
Cholesterol ester transfer protein inhibitor.
Synthesis impurity