Description
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Cas No. | 1876467-74-1 |
|---|---|
| Purity | ≥99% |
| Formula | C20H21N7O |
| Formula Wt. | 375.44 |
| IUPAC Name | 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine |
| Synonym | BAY 1895344, BAY1895344 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wengner A., Siemeister G. et al. ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. 77(13 Suppl):Abstract nr 836 (2017).
Ras inhibitor.
Mycotoxin produced by species of Aspergillus; D...
Endogenous calcitonin-family peptide, involved ...
Peptide; galanin antagonist.
Fluoroquinolone; topoisomerase IV and bacterial...
Steroidogenesis inhibitor
Bisphosphonate; squalene synthase inhibitor.
Endogenous neuropeptide involved in hormone rel...
Mouse selective STING agonist.
PLK4 inhibitor.
Nucleoside (deoxycytidine) analog; ribonucleoti...
Water-soluble parthenolide analog; NF-κB inhib...
Opioid peptide; μOR agonist.
Imidazole; 14-α demethylase inhibitor.
Dihydropyrazine found in Ligusticum walliichi. ...
Inhibitor of VEGFR and FGFR.
Flavanol originally found in Camilla (green tea...
5-Lipoxygenase inhibitor.
Polyphenol found in olive oil, antioxidant.