Description
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
Product Unit Size | Cost | Quantity | Stock |
---|
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
Cas No. | 1876467-74-1 |
---|---|
Purity | ≥99% |
Formula | C20H21N7O |
Formula Wt. | 375.44 |
IUPAC Name | 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine |
Synonym | BAY 1895344, BAY1895344 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Wengner A., Siemeister G. et al. ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. 77(13 Suppl):Abstract nr 836 (2017).
Enone.
Peptide, derivative of AT I, cleavage product o...
Antioxidant, vitamin E derivative found in vege...
Synthetic quinone CoQ analog, promotes mitochon...
β-lactam cephalosporin; penicillin binding pro...
Endogenous calcitonin-family peptide, involved ...
Alkaline phosphatase substrate used to quantify...
Cannabinoid receptor 2 selective agonist.
Aurora kinase A inhibitor
Thiazide diuretic; NCCT inhibitor, carbonic anh...
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Cdc42 inhibitor.
Antimicrobial peptide found in bee and wasp ven...
Camptothecin derivative; topoisomerase I inhibi...
PLK1 inhibitor.
Fluoroquinolone; topoisomerase IV and bacterial...
Diterpene found in brewed, unfiltered coffee; F...
Abl inhibitor.
HIV protease, GLUT4, calpain inhibitor.
Synthetic cafestol derivative.