Description
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Cas No. | 1876467-74-1 |
|---|---|
| Purity | ≥99% |
| Formula | C20H21N7O |
| Formula Wt. | 375.44 |
| IUPAC Name | 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine |
| Synonym | BAY 1895344, BAY1895344 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wengner A., Siemeister G. et al. ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. 77(13 Suppl):Abstract nr 836 (2017).
Anxiolytic-like agent that stimulates angiogene...
Lincosamide; ribosomal translocation and protei...
Neuropeptide found in Locusta migratoria.
Thalidomide derivative; cereblon and TNF-α inh...
H+/K+ ATPase inhibitor.
Macrolide antibiotic; peptidyl transferase inhi...
Purine derivative; CDK inhibitor.
Synthetic peptide hormone.
Alkaloid found in Galanthus, Narcissus, Leucoju...
Diterpene found in Salvia.
Sulfonylurea; ATP-sensitive K+ channel blocker....
PDGFR inhibitor.
Neuraminidase inhibitor.
Inhibits HCV replication
mTOR inhibitor.
Topoisomerase II inhibitor, RPA modulator.
PDE4 inhibitor.
Kavalactone originally found in Piper methystic...
Prenylated flavonoid found in Humulus lupulus.<...
TLR4 inhibitor.