LKT Labs

Biochemicals for Life Science Research

Bombesin

Bombesin

Product ID B5648
Cas No. 31362-50-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $85.00 In stock
2 mg $145.00 In stock
5 mg $275.00 In stock
Bulk Quote

Quicklinks

Description

Bombesin is a gastrin-releasing peptide (GRP) analog that stimulates intestinal function; it was originally found in Bombina toads and binds bombesin receptors (BBRs) and GRP receptors. Mammalian homologs of this compound are neuromedin B and GRP. Bombesin exhibits antiepileptic/anticonvulsant potential, potentiating GABA release by increasing extracellular Ca2+ influx and inducing membrane depolarization through the inhibition of inwardly rectifying (hERG) K+ channels. Bombesin also exhibits anorexigenic and carcinogenic (pro-cancer) activities.

Product Info

Cas No.

31362-50-2
Purity

≥95%
Formula

C71H111N24O18S
Formula Wt.

1619.86
Synonym

2-L-glutamine-6-L-asparagine-Alytesin
Solubility

Soluble in 5% acetic acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B5648 MSDS PDF
Info Sheet

B5648 Info Sheet PDF

References

Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B8070

    2-tert-Butyl-4-Hydroxyanisole

    BHA derivative, antioxidative food and cosmetic...

    ≥99% single isomer
  • I761004

    Itaconic Acid

    Polymer precursor

    ≥99%
  • M3353

    Minocycline Hydrochloride

    Tetracycline; protein translation inhibitor, MM...

    ≥98%
  • G4482

    Glucagon-like Peptide I (7-37)

    Endogenous peptide hormone, GLP-1 fragment, inv...

    ≥95%
  • P0093

    Paclitaxel, semi-synthetic

    Semi-synthetic diterpene originally found in Ta...

    ≥99%
  • S0134

    Saikosaponin D

    Triterpene saponin found in Bupleurum.

    ≥98%
  • T2668

    TGR5 Receptor Agonist

    TGR5 agonist.

    ≥99%
  • T0092

    1-Hydroxybaccatin I

    Diterpene found in Taxus; potential microtubule...

    ≥96%
  • L5749

    Lomefloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • G7444

    GSK-1070916

    AurKB/C inhibitor.

    ≥98%
  • P7218

    Pseudoprotodioscin

    Steroidal saponin found in Tribulus, Trigonella...

    ≥98%
  • C0149

    Calcitonin, salmon

    Endogenous neuropeptide hormone, lowers extrace...

    ≥98%
  • K040009

    KB-0742 dihydrochloride

    CDK9 inhibitor.

    ≥99%
  • I7557

    1-Isothiocyanato-6-(methylsulfonyl)-hexane

    Synthetic ITC, erysolin analog.

    ≥98%
  • O9396

    Oxytetracycline

    Tetracycline; protein translation inhibitor.

    ≥96%
  • I7155

    Isoindigo

    Potential AhR binding agent.

    ≥98%
  • S6000

    Sparfloxacin

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • R0154

    Ranolazine Dihydrochloride

    Nav1.7 and Nav1.8 N1+ channel blocker.

    ≥98%
  • A4935

    6-Aminocaproic Acid

    Protease inhibitor.

    ≥98%
  • S8044

    R,S-Sulforaphane, High Purity

    Phase II enzyme inducer; Nrf2 activator; antiox...

    ≥99%