LKT Labs

Biochemicals for Life Science Research

Bombesin

Bombesin

Product ID B5648
Cas No. 31362-50-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $85.00 In stock
2 mg $145.00 In stock
5 mg $275.00 In stock
Bulk Quote

Quicklinks

Description

Bombesin is a gastrin-releasing peptide (GRP) analog that stimulates intestinal function; it was originally found in Bombina toads and binds bombesin receptors (BBRs) and GRP receptors. Mammalian homologs of this compound are neuromedin B and GRP. Bombesin exhibits antiepileptic/anticonvulsant potential, potentiating GABA release by increasing extracellular Ca2+ influx and inducing membrane depolarization through the inhibition of inwardly rectifying (hERG) K+ channels. Bombesin also exhibits anorexigenic and carcinogenic (pro-cancer) activities.

Product Info

Cas No.

31362-50-2
Purity

≥95%
Formula

C71H111N24O18S
Formula Wt.

1619.86
Synonym

2-L-glutamine-6-L-asparagine-Alytesin
Solubility

Soluble in 5% acetic acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B5648 MSDS PDF
Info Sheet

B5648 Info Sheet PDF

References

Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5278

    Angiotensin III, human

    Endogenous peptide, cleavage product of AT II; ...

    ≥95%
  • P014442

    Palbociclib

    CDK4/6 inhibitor.

    ≥98%
  • P2508

    Phenethyl Isothiocyanate

    ITC found in cruciferous vegetables.

    ≥99%
  • C4535

    Clinafloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • G691343

    Griseofulvin

    Fungistatic

    ≥98%
  • O4402

    Olaparib

    PARP1/2 inhibitor.

    ≥98%
  • T5720

    Tofacitinib Citrate

    JAK1/2/3 inhibitor.

    ≥99%
  • S9755

    (R)-Synephrine

    Synephrine is an endogenous alkaloid.

    ≥98%
  • P0109

    P7C3A20

    Fluorinated aminopropyl carbazole, neuroprotect...

    ≥94%
  • G2868

    Ghrelin, human

    Endogenous peptide hormone, involved in feeding...

    ≥98%
  • X1753

    Xenopsin

    Peptide hormone, neurotensin analog found in am...

    ≥95%
  • B3320

    Bifonazole

    Imidazole; HMG-CoA reductase, 14-α demethylase...

    ≥98%
  • M0374

    Masitinib

    PDGFR and c-Kit inhibitor.

    ≥99%
  • A0964

    Adrenocorticotropic Hormone (1-13), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • N3448

    Nimodipine

    L-type Ca2+ channel blocker.

    ≥98%
  • K0038

    Kahweol Oleate

    Diterpene found in coffee beans.

    ≥98%
  • L9610

    Lycorine Hydrochloride

    Alkaloid found in plants in the Amaryllidaceae ...

    ≥98%
  • V7200

    VS-5584

    PI3K inhibitor.

    ≥98%
  • S3453

    Sinigrin Monohydrate, synthetic

    ITC precursor found in cruciferous vegetables.<...

    ≥98%
  • R1217

    RDEA119

    MEK1/2 inhibitor.

    ≥98%