LKT Labs

Biochemicals for Life Science Research

Bombesin

Bombesin

Product ID B5648
Cas No. 31362-50-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $85.00 In stock
2 mg $145.00 In stock
5 mg $275.00 In stock
Bulk Quote

Quicklinks

Description

Bombesin is a gastrin-releasing peptide (GRP) analog that stimulates intestinal function; it was originally found in Bombina toads and binds bombesin receptors (BBRs) and GRP receptors. Mammalian homologs of this compound are neuromedin B and GRP. Bombesin exhibits antiepileptic/anticonvulsant potential, potentiating GABA release by increasing extracellular Ca2+ influx and inducing membrane depolarization through the inhibition of inwardly rectifying (hERG) K+ channels. Bombesin also exhibits anorexigenic and carcinogenic (pro-cancer) activities.

Product Info

Cas No.

31362-50-2
Purity

≥95%
Formula

C71H111N24O18S
Formula Wt.

1619.86
Synonym

2-L-glutamine-6-L-asparagine-Alytesin
Solubility

Soluble in 5% acetic acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B5648 MSDS PDF
Info Sheet

B5648 Info Sheet PDF

References

Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A484091

    Amcinonide

    Glucocorticoid

    ≥98%
  • H9759

    Hypaconitine

    Diterpene alkaloid found in Aconitum; voltage-g...

    ≥90%
  • H1892

    Hexamethylene Bisacetamide

    HEXIM1 activator.

    ≥99%
  • A4497

    Alyssin Sulfone

    Naturally sourced ITC, sulfonyl analog of sulfo...

    ≥97%
  • E7356

    Esomeprazole Magnesium Trihydrate

    S-isomer of omeprazole; H+/K+ ATPase inhibitor....

    ≥99%
  • D1759

    Deoxynivalenol

    Trichothecene mycotoxin produced by Fusarium.

    ≥98%, TLC
  • N3478

    Nitrendipine

    Calcium channel blocker.

    ≥98%
  • C0151

    α-Calcitonin Gene Related Peptide, human

    Endogenous calcitonin-family peptide, involved ...

    ≥95%
  • U698574

    Urolithin A

    Ellagic acid derivative produced by gut microfl...

    ≥98%
  • L1735

    Levitide

    Antimicrobial peptide found in amphibians.

    ≥95%
  • D3374

    Disulfiram

    Aldehyde dehydrogenase, 26S proteasome, MGMT in...

    ≥98%
  • B1978

    Betulin-3-Acetate

    Pentacyclic triterpene found in various plant s...

    ≥97%
  • A980005

    AZ-5104

    Inhibitor of EGFR.

    ≥98%
  • M1626

    Megestrol Acetate

    Synthetic progestogen, orexigenic.

    ≥98%
  • W4096

    WKYMVM-NH2

    Synthetic peptide; FPRL1 agonist.

    ≥95%
  • I5992

    IOX2

    Prolyl hydroxylase inhibitor.

    ≥98%
  • A1616

    AEE-788

    Inhibitor of EGFR, HER2, VEGFR2, and FLT3.

    ≥98%
  • L1684

    Levonorgestrel

    Synthetic progestogen; contraceptive.

    ≥98%
  • G2869

    Ghrelin, rat

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • M1879

    Metoprolol Tartrate

    β1-adrenergic antagonist.

    ≥98%