LKT Labs

Biochemicals for Life Science Research

Bombesin

Bombesin

Product ID B5648
Cas No. 31362-50-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $85.00 In stock
2 mg $145.00 In stock
5 mg $275.00 In stock
Bulk Quote

Quicklinks

Description

Bombesin is a gastrin-releasing peptide (GRP) analog that stimulates intestinal function; it was originally found in Bombina toads and binds bombesin receptors (BBRs) and GRP receptors. Mammalian homologs of this compound are neuromedin B and GRP. Bombesin exhibits antiepileptic/anticonvulsant potential, potentiating GABA release by increasing extracellular Ca2+ influx and inducing membrane depolarization through the inhibition of inwardly rectifying (hERG) K+ channels. Bombesin also exhibits anorexigenic and carcinogenic (pro-cancer) activities.

Product Info

Cas No.

31362-50-2
Purity

≥95%
Formula

C71H111N24O18S
Formula Wt.

1619.86
Synonym

2-L-glutamine-6-L-asparagine-Alytesin
Solubility

Soluble in 5% acetic acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B5648 MSDS PDF
Info Sheet

B5648 Info Sheet PDF

References

Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • Q8134

    Quinapril Hydrochloride

    ACE inhibitor.

    ≥98%
  • C577524

    Concanamycin A

    Macrolide lactone antibiotic.

    ≥98%
  • M1565

    S-Methyl-L-cysteine-S-oxide

    Organosulfur found in cruciferous vegetables; a...

    ≥95%
  • S020665

    Saquinavir

    Protease inhibitor

    ≥99%
  • G720004

    GS-4997

    ASK1 inhibitor.

    ≥99%
  • R1878

    Retinyl Acetate

    Vitamin A derivative, acetate ester of retinol....

    ≥98%
  • T3202

    Tianeptine

    μOR and δOR agonist, D2/D3 DA potentiator.

    ≥98%
  • A1333

    Adipokinetic Hormone II from Schistocera gregaria

    Neuropeptide found in Schistocera gregaria.

    ≥95%
  • R2812

    Recombinant HIV-1 gp-120

    Recombinant HIV glycoprotein antigen fragment.<...

    ≥95%
  • N3452

    Nimustine Hydrochloride

    Nitrosourea, DNA cross-linker.

    ≥97%
  • E4416

    Eledoisin

    Peptide, substance P analog; NK agonist.

    ≥95%
  • D5753

    Donepezil Hydrochloride

    GSK3 and AChE inhibitor, potential σ1 agonist....

    ≥98%
  • P1622

    Pefloxacin Methanesulfonate Dihydrate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • E8419

    Everolimus

    mTORC1 inhibitor.

    ≥98%
  • J6400

    (+)-JQ-1

    Triazolothienodiazepine; BRD inhibitor.

    ≥99%
  • P0370

    Paromomycin Sulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • D3221

    Difluoromethylornithine Hydrochloride Monohydrate

    Ornithine decarboxylase inhibitor.

    ≥98%
  • D490280

    DMH-1

    Inhibitor of BMP.

    ≥99%
  • C4756

    Cloxacillin Sodium Monohydrate

    β-lactam; penicillin binding protein inhibitor...

    ≥98%
  • P2856

    Phorbol-12,13-dibutyrate

    PKC and PKD activator, carcinogen.

    ≥98%