LKT Labs

Biochemicals for Life Science Research

Bombesin

Bombesin

Product ID B5648
Cas No. 31362-50-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $167.40 In stock
2 mg $259.60 In stock
5 mg $502.30 In stock
Bulk Quote

Quicklinks

Description

Bombesin is a gastrin-releasing peptide (GRP) analog that stimulates intestinal function; it was originally found in Bombina toads and binds bombesin receptors (BBRs) and GRP receptors. Mammalian homologs of this compound are neuromedin B and GRP. Bombesin exhibits antiepileptic/anticonvulsant potential, potentiating GABA release by increasing extracellular Ca2+ influx and inducing membrane depolarization through the inhibition of inwardly rectifying (hERG) K+ channels. Bombesin also exhibits anorexigenic and carcinogenic (pro-cancer) activities.

Product Info

Cas No.

31362-50-2
Purity

≥95%
Formula

C71H111N24O18S
Formula Wt.

1619.86
Synonym

2-L-glutamine-6-L-asparagine-Alytesin
Solubility

Soluble in 5% acetic acid.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B5648 MSDS PDF
Info Sheet

B5648 Info Sheet PDF

References

Zhang HP, Xiao Z, Cilz NI, et al. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014 Jan;24(1):21-31. PMID: 23966303.

Weber HC. Regulation and signaling of human bombesin receptors and their biological effects. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):66-71. PMID: 19115523.

Yamada K, Wada E, Wada K. Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice. Ann Med. 2000 Nov;32(8):519-29. PMID: 11127929.

Ohlsson B, Fredäng N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol. 1999 Dec;34(12):1224-9. PMID: 10636070.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D3215

    Didymin

    Flavonoid glycoside found in citrus fruit.

    ≥98%
  • I0502

    Ibandronate Sodium Monohydrate

    Bisphosphonate.

    ≥98%
  • C022682

    2-Carbomethoxy-3-thiophenesulfonyl Chloride

    Building block

    ≥98%
  • L960012

    LY-3214996

    ERK1/2 inhibitor.

    ≥98%
  • P9767

    Pyriproxyfen

    Juvenile insect hormone mimic.

    ≥95%
  • H5748

    D,L-Homocysteine Thiolactone Hydrochloride

    Heterocyclic derivative of cysteine, alters pro...

    ≥99%
  • M1579

    Methazolamide

    Carbonic anhydrase inhibitor.

    ≥98%
  • N176498

    Nemorosone

    Found in the propolis of honey bees.

    ≥99%
  • B1640

    Benzydamine Hydrochloride

    NSAID; PG synthetase inhibitor.

    ≥98%
  • Y4802

    YM-201636

    PIKfyve inhibitor.

    ≥98%
  • T0120

    2′,7-bis(triethylsilyl)taxol

    Synthesis intermediate

    ≥98%
  • M002698

    M2698

    Dual inhibitor of p70S6K and Akt.

    ≥99%
  • G7342

    GSK-2126458

    p110α PI3K and mTOR inhibitor.

    ≥99%
  • F8147

    Fulvestrant

    Induces ER degradation.

    ≥98%
  • H965142

    Hydrolyzed Fumonisin B1

    Mycotoxin produced by Fusarium fungi that infec...

    ≥99% by ELSD
  • M9608

    Myclobutanil

    14-α demethylase inhibitor.

    ≥97%
  • M3377

    Mitomycin C

    Alkaloid produced by Streptomyces, DNA cross-li...

    ≥98%
  • E5201

    Enalapril Maleate

    ACE inhibitor.

    ≥98%
  • D3320

    Difenoconazole

    Triazole; 14-α demethylase inhibitor, potentia...

    ≥98%
  • S7872

    Stresscopin-Related Peptide, human

    Peptide, urocortin II analog; CRFR2 agonist.

    ≥95%