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Butylated hydroxyanisole (BHA) exhibits antioxidative and anticancer activities. BHA is commercially used as a food additive or preservative, as its free radical scavenging ability stabilizes free radicals and prevents food spoilage. BHS also increases activity of superoxide dismutase (SOD) in breast cancer cells, inhibiting cellular proliferation. This compound may also display carcinogenic potential.
| Cas No. | 25013-16-5 |
|---|---|
| Purity | ≥96% |
| Formula | C11H16O2 |
| Formula Wt. | 180.24 |
| Chemical Name | (1,1-Dimethylethyl)-4-methoxyphenol |
| IUPAC Name | 2-tert-butyl-4-methoxyphenol AND 3-tert-butyl-4-methoxyphenol (mixture) |
| Synonym | BHA, Antrancine 12, Embanox, Nipantiox 1-F, Sustane 1-F, Tenox BHA |
| Melting Point | 48-55°C |
| Solubility | Soluble in >50% alcohol, ethanol (150 mg/mL), propylene glycol, fats or oils. Insoluble in water. |
| Appearance | White Powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Singh B, Bhat HK. Superoxide dismutase 3 is induced by antioxidants, inhibits oxidative DNA damage and is associated with inhibition of estrogen-induced breast cancer. Carcinogenesis. 2012 Dec;33(12):2601-10. PMID: 23027624.
Criado S, Allevi C, Ceballos C, et al. Visible-light promoted degradation of the commercial antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT): a kinetic study. Redox Rep. 2007;12(6):282-8. PMID: 17961300.