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Cardiogenol C Hydrochloride

Cardiogenol C Hydrochloride

Product ID C0369
Cas No. 671225-39-1; 1049741-55-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $75.10 In stock
5 mg $225.40 In stock
25 mg $676.10 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
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  • Downloads
  • References
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Description

Cardiogenol C induces cardiomyogenic effects in pluripotent P19 embryonic carcinoma cells. Cardiogenol C also significantly increases atrial natriuretic factor and Nkx2.5 expression and induces expression of cardiac Nav1.5 channels in C2C12 skeletal myoblasts. In multipotent stem cells from murine hair follicles, Cardiogenol C has also been shown to induce transdifferentiation into cardiomyocyte-like cells.

Product Info

Cas No.

671225-39-1; 1049741-55-0

Purity

≥98%

Formula

C13H16N4O2 • HCl

Formula Wt.

296.76

Chemical Name

2-({2-[(4-Methoxyphenyl)amino]-4-pyrimidinyl}amino)ethanol hydrochloride

IUPAC Name

2-[[2-(4-methoxyanilino)pyrimidin-4-yl]amino]ethanol;hydrochloride

Solubility

100mM in Water 100mM in DMSO

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C0369 MSDS PDF

Info Sheet

C0369 Info Sheet PDF

References

Mike AK, Koenig X, Koley M, et al. Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Cell Physiol Biochem. 2014;33(1):205-221. PMID: 24481283.

Skalova S, Svadlakova T, Qureshi WMS, et al. Induced pluripotent stem cells and their use in cardiac and neural regenerative medicine. Int J Mol Sci. 2015 Feb;16(2):4043-4067. PMID: 25689424.

Christ GJ, Saul JM, Furth ME, Andersson KE. The pharmacology of regenerative medicine. Pharmacol Rev. 2013 Jul;65(3):1091-1133. PMID: 23818131.

Yau W, Tang MK, Chen E, et al. Cardiogenol C can induce mouse hair bulge progenitor cells to transdifferentiate into cardiomyocyt-like cells. Proteome Sci. 2011;9:3. PMID: 21247432.

Custom Order

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