Catharanthine Tartrate

Name: Catharanthine Tartrate
SKU: C0378
Availability: InStock

Product ID C0378

Cas No. 4168-17-6

Purity ≥97%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Catharanthine is an alkaloid found in Catharanthus that is a chemical precursor in the synthesis of vinca alkaloids such as vinblastine and vincristine. Catharanthine displays weak anti-mitotic activity, binding tubulin poorly. Catharanthine exhibits anti-parasitic, vasodilatory, and antihypertensive activities. This compound shows antimalarial benefit against species of Plasmodium. In vivo, catharanthine inhibits voltage-gated Ca2+ channel currents, decreasing blood pressure and heart rate.

Product Info

Cas No.	4168-17-6
Purity	≥97%
Formula	C₂₁H₂₄N₂O₂ • C₄H₆O₆
Formula Wt.	486.52
Chemical Name	3,4-Didehydroibogamine-18-carboxylic acid methyl ester
IUPAC Name	2,3-dihydroxybutanedioic acid;methyl (1R,15R,18R)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8,16-pentaene-1-carboxylate
Synonym	Catharanthine
Melting Point	126-128°C
Solubility	Soluble in ethanol.
Appearance	White Powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	C0378 MSDS PDF
Info Sheet	C0378 Info Sheet PDF

References

Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Catharanthine Tartrate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Benzyl Selenocyanate

Catharanthine Sulfate

Sinomenine Hydrochloride

Astragaloside IV

Efaroxan Hydrochloride

PHT-427

Tianeptine Sodium Hydrate

S-Equol

AG-1517

Cysteamine Hydrochloride

S-(−)-Schisandrin B

Icaritin

Dipropyl Disulfide

2-tert-Butyl-4-Hydroxyanisole

K252a

RGDS

AZD-7648

(Z)-1,-Bis(2-methoxy-5-(trifluoromethyl)phenyl)diazene oxide

GNE-7915

N-Acetyl-S-(N′-benzylthiocarbamoyl)-L-cysteine

Footer