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Chartreusin

Chartreusin

Product ID C2803
Cas No. 6377-18-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $263.00 Please Inquire
25 mg $976.50 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Chartreusin is an antibiotic compound that also exhibits anticancer activity. Chartreusin binds GC-rich DNA sequences, inhibiting synthesis of RNA and causing free radical accumulation.

Product Info

Cas No.

6377-18-0

Purity

≥98%

Formula

C32H32O14

Formula Wt.

640.6

Chemical Name

Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 10-((6-deoxy-2-O-(6-deoxy-3-O-methyl-alpha-D- galactopyranosyl)-beta-D-galactopyranosyl)oxy)-6-hydroxy-1- methyl- (9CI)

IUPAC Name

3-[(2S,3R,4S,5R,6R)-3-[(2R,3R,4S,5S,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4,5-dihydroxy-6-methyloxan-2-yl]oxy-8-hydroxy-15-methyl-11,18-dioxapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2(7),3,5,8,12(20),13,15-octaene-10,17-dione

Synonym

Lambdamycin, NSC-5159.

Melting Point

184-186°C

Solubility

Soluble in acetone. Practically insoluble in water.

Appearance

Yellow sold

Shipping and Storage

Store Temp

-20°C

Ship Temp

Blue Ice

Downloads

MSDS

C2803 MSDS PDF

Info Sheet

C2803 Info Sheet PDF

References

Portugal J. Chartreusin, elsamicin A and related anti-cancer antibiotics. Curr Med Chem Anticancer Agents. 2003 Nov;3(6):411-20. PMID: 14529449.

Uramoto M, Kusano T, Nishio T, et al. Specific binding of chartreusin, an antitumor antibiotic, to DNA. FEBS Lett. 1983 Mar 21;153(2):325-8. PMID: 6311618.

Yagi M, Nishimura T, Suzuki H, et al. Chartreusin, an antitumor glycoside antibiotic, induces DNA strand scission. Biochem Biophys Res Commun. 1981 Feb 12;98(3):642-7. PMID: 7225117.

Custom Order

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